National Institute of Neurological Disorders and Stroke (NINDS) Clinical Trials
Sponsors / National Institute of Neurological Disorders and Stroke (NINDS)
ClinicalTrials.gov lists 885 trials for which National Institute of Neurological Disorders and Stroke (NINDS) is named as lead sponsor. The portfolio currently includes 114 recruiting studies, 26 active non-recruiting studies, and 644 completed studies. 65 trials in this portfolio were terminated or withdrawn before completion. The most common reasons cited for termination include slow or insufficient recruitment, efficacy or futility findings. Cumulative planned enrollment across all listed trials is 190,836 participants. These counts reflect the current state of the public ClinicalTrials.gov registry.
Termination reasons: Other72% · Recruitment12% · Efficacy8% · PI/or_Site3% · Funding3% · Safety2%
Recent Terminations
- Parkinson Disease Dementia"Company closure"
- Muscle Spasticity"Slow enrollment"
- NCT05547412 Stopped Jan 2023Acute Ischemic Stroke"enrollment, administrative/finance"
- NCT03867435 Stopped Nov 2021Myotonic Dystrophy Type-1"PI left the NIH"
- Migraine"due to COVID-19"
- NCT03206112 Stopped Apr 2020Focal Dystonia"PI leaving the NIH"
- Infant Development"COVID-19 shutdown"
- Cerebrospinal Fluid"Difficulty with recruitment and participant accrual due to study eligibility criteria and required study procedures (e.g., multiple lumbar punctures)."
- NCT03263000 Stopped Apr 2019Blepharospasm"Protocol could not be carried out to achieve the aims of the study"
- Emotions"Competition with other ongoing projects with this population."
Active Trials (26 total)
- NCT00001248
- NCT00004577
- NCT00009243
- NCT00018889
- NCT00598351
- NCT01150708
- NCT01568658
- NCT01730131
- NCT02119611
- NCT02531880
- NCT02639325
- NCT02784210
- NCT02911103
- NCT05375812
- NCT06615973
- NCT06707207
- NCT07137442
- NCT07204977
- NCT07511049
- NCT05849467