Completed PHASE3 INTERVENTIONAL NCT00000658

A Phase III Randomized Trial of Low-Dose Versus Standard-Dose mBACOD Chemotherapy With rGM-CSF for Treatment of AIDS-Associated Non-Hodgkin's Lymphoma

Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)

Conditions HIV Infections Lymphoma, Non-Hodgkin

Interventions Allopurinol Bleomycin sulfate Cyclophosphamide Cytarabine Dexamethasone Doxorubicin hydrochloride Leucovorin calcium Methotrexate Sargramostim Vincristine sulfate

Updated 8 times since 2017 Last updated: Oct 26, 2021 Completion: Feb 29, 1996

This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

A PHASE3 clinical study on HIV Infections and Lymphoma, Non-Hodgkin, this trial is completed. The trial is conducted by National Institute of Allergy and Infectious Diseases (NIAID) and has accumulated 8 data snapshots since 2026. Oncology trials at this stage typically focus on safety, tolerability, and early efficacy signals.

Status Flow

Change History

8 versions recorded

Sep 2025 — Present [monthly]

Completed PHASE3
Sep 2024 — Sep 2025 [monthly]

Completed PHASE3
Jul 2024 — Sep 2024 [monthly]

Completed PHASE3
Dec 2021 — Jul 2024 [monthly]

Completed PHASE3
Jan 2021 — Dec 2021 [monthly]

Completed PHASE3

▶ Show 3 earlier versions

Jun 2018 — Jan 2021 [monthly]

Completed PHASE3
Feb 2017 — Jun 2018 [monthly]

Completed PHASE3
Jan 2017 — Feb 2017 [monthly]

Completed PHASE3

First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:

National Institute of Allergy and Infectious Diseases (NIAID)
Schering-Plough

Data source: National Institute of Allergy and Infectious Diseases (NIAID)

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations

Aurora, United States , Baltimore, United States , Boston, United States , Buffalo, United States , Chapel Hill, United States , Chicago, United States , Cleveland, United States , Columbus, United States , Indianapolis, United States , Los Angeles, United States and 6 more locations