Antiviral Activity of and Resistance to Lamivudine in Combination With Zidovudine, Stavudine, or Didanosine
A Phase II, Randomized Study of the Antiviral Activity and Resistance Interactions of Lamivudine (3TC) in Combination With Zidovudine (AZT), Stavudine (d4T), or Didanosine (ddI) Versus Monotherapy With ddI or d4T in HIV-Infected Individuals With 200 - 600 CD4+ Cells/mm3 and No Previous Nucleoside Experience
Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)
A PHASE2 clinical study on HIV Infections, this trial is completed. The trial is conducted by National Institute of Allergy and Infectious Diseases (NIAID) and has accumulated 7 data snapshots since 2026. Infectious disease trials contribute critical data for public health response and treatment development.
Change History
7 versions recorded-
Sep 2025 — Present [monthly]
Completed PHASE2
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Sep 2024 — Sep 2025 [monthly]
Completed PHASE2
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Jul 2024 — Sep 2024 [monthly]
Completed PHASE2
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Dec 2021 — Jul 2024 [monthly]
Completed PHASE2
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Jan 2021 — Dec 2021 [monthly]
Completed PHASE2
▶ Show 2 earlier versions
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Jun 2018 — Jan 2021 [monthly]
Completed PHASE2
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Jan 2017 — Jun 2018 [monthly]
Completed PHASE2
First recorded
Eligibility Summary
No eligibility information available.
Contact Information
- National Institute of Allergy and Infectious Diseases (NIAID)
For direct contact, visit the study record on ClinicalTrials.gov .
Study Locations
Aurora, United States, Baltimore, United States, Birmingham, United States, Boston, United States, Buffalo, United States, Chapel Hill, United States, Charlotte, United States, Chicago, United States, Cleveland, United States, Columbus, United States and 15 more location s