deltatrials
Completed PHASE2 INTERVENTIONAL 2-arm NCT00001626

Comparing Therapies for the Treatment of Severe Aplastic Anemia

A Randomized Trial of Antithymocyte Globulin and Cyclosporine Versus Cyclophosphamide and Cyclosporine in the Treatment of Severe Aplastic Anemia

Sponsor: National Heart, Lung, and Blood Institute (NHLBI)

Conditions Severe Aplastic Anemia (SAA)
Interventions antithymocyte globulin cyclophosphamide cyclosporine
Updated 15 times since 2017 Last updated: Sep 21, 2020 Started: Jun 2, 1997 Primary completion: Feb 20, 2001 Completion: Mar 3, 2008
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

This PHASE2 trial investigates Severe Aplastic Anemia (SAA) and is currently completed. National Heart, Lung, and Blood Institute (NHLBI) leads this study, which shows 15 recorded versions since 1997 — indicating substantial longitudinal coverage. The change history captured here reflects the iterative nature of clinical trial conduct.

Status Flow

~Jan 2017 – ~Feb 2017 · 31 days · monthly snapshot~Feb 2017 – ~Jun 2018 · 16 months · monthly snapshot~Jun 2018 – ~Jul 2018 · 30 days · monthly snapshot~Jul 2018 – ~Sep 2018 · 2 months · monthly snapshot~Sep 2018 – ~Oct 2018 · 30 days · monthly snapshot~Oct 2018 – ~Nov 2018 · 31 days · monthly snapshot~Nov 2018 – ~Jan 2019 · 2 months · monthly snapshot~Jan 2019 – ~Jun 2019 · 5 months · monthly snapshot~Jun 2019 – ~Aug 2019 · 2 months · monthly snapshot~Aug 2019 – ~Oct 2019 · 2 months · monthly snapshot~Oct 2019 – ~Oct 2020 · 12 months · monthly snapshot~Oct 2020 – ~Jan 2021 · 3 months · monthly snapshot~Jan 2021 – ~Jul 2024 · 42 months · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – present · 22 months · monthly snapshot

Change History

15 versions recorded

  1. Sep 2024 — Present [monthly]

    Completed PHASE2

  2. Jul 2024 — Sep 2024 [monthly]

    Completed PHASE2

  3. Jan 2021 — Jul 2024 [monthly]

    Completed PHASE2

  4. Oct 2020 — Jan 2021 [monthly]

    Completed PHASE2

  5. Oct 2019 — Oct 2020 [monthly]

    Completed PHASE2

▶ Show 10 earlier versions

  1. Aug 2019 — Oct 2019 [monthly]

    Completed PHASE2

  2. Jun 2019 — Aug 2019 [monthly]

    Completed PHASE2

  3. Jan 2019 — Jun 2019 [monthly]

    Completed PHASE2

  4. Nov 2018 — Jan 2019 [monthly]

    Completed PHASE2

  5. Oct 2018 — Nov 2018 [monthly]

    Completed PHASE2

    Phase: PHASE3 → PHASE2

  6. Sep 2018 — Oct 2018 [monthly]

    Completed PHASE3

  7. Jul 2018 — Sep 2018 [monthly]

    Completed PHASE3

  8. Jun 2018 — Jul 2018 [monthly]

    Completed PHASE3

  9. Feb 2017 — Jun 2018 [monthly]

    Completed PHASE3

  10. Jan 2017 — Feb 2017 [monthly]

    Completed PHASE3

    First recorded

Jun 1997

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • National Heart, Lung, and Blood Institute (NHLBI)
Data source: National Institutes of Health Clinical Center (CC)

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations