Completed PHASE3 INTERVENTIONAL 2-arm NCT00002633

Hormone Therapy With or Without Surgery or Radiation Therapy in Treating Patients With Prostate Cancer

Phase III Randomized Trial Comparing Total Androgen Blockade Versus Total Androgen Blockade Plus Pelvic Irradiation in Clinical Stage T3-4, N0, M0 Adenocarcinoma of the Prostate

Sponsor: Eastern Cooperative Oncology Group

Conditions Prostate Cancer

Interventions bicalutamide buserelin flutamide goserelin leuprolide acetate nilutamide orchiectomy radiation therapy

Updated 9 times since 2017 Last updated: Apr 1, 2020 Started: Feb 8, 1995 Primary completion: Sep 23, 2011 Completion: Jan 6, 2012

This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Listed as NCT00002633, this PHASE3 trial focuses on Prostate Cancer and remains completed. Sponsored by Eastern Cooperative Oncology Group, it has been updated 9 times since 1995, reflecting limited change activity. This study contributes to the evolving evidence base for cancer treatment protocols.

Status Flow

Change History

9 versions recorded

Sep 2025 — Present [monthly]

Completed PHASE3
Sep 2024 — Sep 2025 [monthly]

Completed PHASE3
Jul 2024 — Sep 2024 [monthly]

Completed PHASE3
May 2023 — Jul 2024 [monthly]

Completed PHASE3
Jan 2021 — May 2023 [monthly]

Completed PHASE3

▶ Show 4 earlier versions

May 2020 — Jan 2021 [monthly]

Completed PHASE3
Jun 2018 — May 2020 [monthly]

Completed PHASE3
Feb 2017 — Jun 2018 [monthly]

Completed PHASE3
Jan 2017 — Feb 2017 [monthly]

Completed PHASE3

First recorded

Feb 1995

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:

Eastern Cooperative Oncology Group
Medical Research Council
NCIC Clinical Trials Group
National Cancer Institute (NCI)
SWOG Cancer Research Network

Data source: Canadian Cancer Trials Group

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations

Edmonton, Canada , Greater Sudbury, Canada , Halifax, Canada , Hamilton, Canada , Kingston, Canada , London, Canada , Montreal, Canada , Ottawa, Canada , Saskatoon, Canada , Surrey, Canada and 4 more locations