deltatrials
Completed PHASE2 NCT00002643

Combination Chemotherapy in Treating Patients With Newly Diagnosed Metastatic Ewing's Sarcoma or Primitive Neuroectodermal Tumor

INTENSIVE THERAPY WITH GROWTH FACTOR SUPPORT FOR PATIENTS WITH EWING'S TUMOR METASTATIC AT DIAGNOSIS: A PEDIATRIC ONCOLOGY GROUP PHASE II STUDY

Sponsor: Children's Cancer Group

Conditions Neutropenia Sarcoma
Interventions amifostine trihydrate conventional surgery cyclophosphamide doxorubicin hydrochloride etoposide filgrastim ifosfamide low-LET cobalt-60 gamma ray therapy low-LET electron therapy low-LET photon therapy topotecan hydrochloride vincristine sulfate
Updated 7 times since 2017 Last updated: Jan 31, 2013 Started: Apr 30, 1995 Primary completion: Jun 30, 2003

This PHASE2 trial investigates Neutropenia and Sarcoma and is currently completed. Children's Cancer Group leads this study, which shows 7 recorded versions since 1995 — indicating limited longitudinal coverage. As an oncology study, it adds to the longitudinal record of treatment development for this indication.

Change History

7 versions recorded

  1. Sep 2025 — Present [monthly]

    Completed PHASE2

  2. Sep 2024 — Sep 2025 [monthly]

    Completed PHASE2

  3. Jul 2024 — Sep 2024 [monthly]

    Completed PHASE2

  4. Jan 2021 — Jul 2024 [monthly]

    Completed PHASE2

  5. Jun 2018 — Jan 2021 [monthly]

    Completed PHASE2

▶ Show 2 earlier versions

  1. Feb 2017 — Jun 2018 [monthly]

    Completed PHASE2

  2. Jan 2017 — Feb 2017 [monthly]

    Completed PHASE2

    First recorded

Apr 1995

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Children's Cancer Group
  • National Cancer Institute (NCI)
Data source: National Cancer Institute (NCI)

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations

Ann Arbor, United States, Asheville, United States, Chapel Hill, United States, Charlottesville, United States, Chicago, United States, Cincinnati, United States, Cleveland, United States, Columbus, United States, Dallas, United States, Denver, United States and 34 more location s