deltatrials
Completed PHASE3 NCT00002708

Radiation Therapy With or Without Radiosurgery in Treating Patients With Brain Metastases

A PHASE III TRIAL COMPARING WHOLE BRAIN IRRADIATION WITH VERSUS WITHOUT STEREOTACTIC RADIOSURGERY BOOST FOR PATIENTS WITH ONE TO THREE UNRESECTED BRAIN METASTASES

Sponsor: National Cancer Institute (NCI)

Conditions Metastatic Cancer
Interventions radiation therapy stereotactic radiosurgery surgical procedure
Updated 6 times since 2017 Last updated: Nov 18, 2013 Started: Jan 31, 1996 Primary completion: Jan 31, 2002 Completion: Dec 31, 2004

Listed as NCT00002708, this PHASE3 trial focuses on Metastatic Cancer and remains completed. Sponsored by National Cancer Institute (NCI), it has been updated 6 times since 1996, reflecting limited change activity. This study contributes to the evolving evidence base for cancer treatment protocols.

Change History

6 versions recorded

  1. Sep 2025 — Present [monthly]

    Completed PHASE3

  2. Sep 2024 — Sep 2025 [monthly]

    Completed PHASE3

  3. Jul 2024 — Sep 2024 [monthly]

    Completed PHASE3

  4. Jan 2021 — Jul 2024 [monthly]

    Completed PHASE3

  5. Jun 2018 — Jan 2021 [monthly]

    Completed PHASE3

▶ Show 1 earlier version

  1. Jan 2017 — Jun 2018 [monthly]

    Completed PHASE3

    First recorded

Jan 1996

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • National Cancer Institute (NCI)
  • Radiation Therapy Oncology Group
Data source: Radiation Therapy Oncology Group

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations

Akron, United States, Albany, United States, Albuquerque, United States, Allentown, United States, Amarillo, United States, Anchorage, United States, Anderson, United States, Ann Arbor, United States, Annapolis, United States, Arlington Heights, United States and 188 more location s