Completed PHASE3 INTERVENTIONAL 2-arm NCT00002716

Combination Chemotherapy in Treating Patients With Liver Metastases From Colorectal Cancer

PHASE III STUDY OF HEPATIC ARTERY FLOXURIDINE (FUDR), LEUCOVORIN (LV), AND DEXAMETHASONE (DEX) VERSUS SYSTEMIC 5-FLUOROURACIL (5-FU) AND LEUCOVORIN (LV) AS TREATMENT FOR HEPATIC METASTASES FROM COLORECTAL CANCER

Sponsor: Alliance for Clinical Trials in Oncology

Conditions Colorectal Cancer Metastatic Cancer

Interventions conventional surgery dexamethasone floxuridine fluorouracil laparotomy leucovorin calcium

Updated 6 times since 2017 Last updated: Jul 12, 2016 Started: Jan 31, 1996 Primary completion: Mar 31, 2006 Completion: Aug 31, 2006

This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

A PHASE3 clinical study on Colorectal Cancer and Metastatic Cancer, this trial is completed. The trial is conducted by Alliance for Clinical Trials in Oncology and has accumulated 6 data snapshots since 1996. Oncology trials at this stage typically focus on safety, tolerability, and early efficacy signals.

Status Flow

Change History

6 versions recorded

Jan 2026 — Present [monthly]

Completed PHASE3
Sep 2024 — Present [monthly]

Completed PHASE3
Jul 2024 — Sep 2024 [monthly]

Completed PHASE3
Jan 2021 — Jul 2024 [monthly]

Completed PHASE3
Jun 2018 — Jan 2021 [monthly]

Completed PHASE3

▶ Show 1 earlier version

Jan 2017 — Jun 2018 [monthly]

Completed PHASE3

First recorded

Jan 1996

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:

Alliance for Clinical Trials in Oncology
National Cancer Institute (NCI)

Data source: Alliance for Clinical Trials in Oncology

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations

Albuquerque, United States , Cedar Rapids, United States , Cleveland, United States , Des Moines, United States , Green Bay, United States , Hershey, United States , Lima, Peru , Papillion, United States , Philadelphia, United States , San Juan, Puerto Rico and 1 more location