deltatrials
Completed PHASE3 INTERVENTIONAL 2-arm NCT00003857

Radiation Therapy With or Without Optional Tamoxifen in Treating Women With Ductal Carcinoma in Situ

Phase III Trial of Tamoxifen Alone vs. Tamoxifen Plus Radiation Therapy for Good Risk Duct Carcinoma In-Situ (DCIS) of the Female Breast

Sponsor: Cancer and Leukemia Group B

Conditions Breast Cancer
Updated 12 times since 2017 Last updated: May 23, 2022 Started: Dec 31, 1999 Primary completion: Feb 29, 2004 Completion: May 20, 2022
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Listed as NCT00003857, this PHASE3 trial focuses on Breast Cancer and remains completed. Sponsored by Cancer and Leukemia Group B, it has been updated 12 times since 1999, reflecting substantial change activity. This study contributes to the evolving evidence base for cancer treatment protocols.

Status Flow

~Jan 2017 – ~Feb 2017 · 31 days · monthly snapshotActive Not Recruiting~Feb 2017 – ~Jun 2017 · 4 months · monthly snapshotActive Not Recruiting~Jun 2017 – ~Jun 2018 · 12 months · monthly snapshotActive Not Recruiting~Jun 2018 – ~Sep 2018 · 3 months · monthly snapshotActive Not Recruiting~Sep 2018 – ~Dec 2019 · 15 months · monthly snapshotActive Not Recruiting~Dec 2019 – ~Nov 2020 · 11 months · monthly snapshotActive Not Recruiting~Nov 2020 – ~Jan 2021 · 2 months · monthly snapshotActive Not Recruiting~Jan 2021 – ~Jun 2022 · 17 months · monthly snapshotActive Not Recruiting~Jun 2022 – ~Jul 2024 · 25 months · monthly snapshotCompleted~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshotCompleted~Sep 2024 – ~Sep 2025 · 12 months · monthly snapshotCompleted~Sep 2025 – present · 8 months · monthly snapshotCompleted

Change History

12 versions recorded
  1. Sep 2025 — Present [monthly]

    Completed PHASE3

  2. Sep 2024 — Sep 2025 [monthly]

    Completed PHASE3

  3. Jul 2024 — Sep 2024 [monthly]

    Completed PHASE3

  4. Jun 2022 — Jul 2024 [monthly]

    Completed PHASE3

    Status: Active Not RecruitingCompleted

  5. Jan 2021 — Jun 2022 [monthly]

    Active Not Recruiting PHASE3

Show 7 earlier versions
  1. Nov 2020 — Jan 2021 [monthly]

    Active Not Recruiting PHASE3

  2. Dec 2019 — Nov 2020 [monthly]

    Active Not Recruiting PHASE3

  3. Sep 2018 — Dec 2019 [monthly]

    Active Not Recruiting PHASE3

  4. Jun 2018 — Sep 2018 [monthly]

    Active Not Recruiting PHASE3

  5. Jun 2017 — Jun 2018 [monthly]

    Active Not Recruiting PHASE3

  6. Feb 2017 — Jun 2017 [monthly]

    Active Not Recruiting PHASE3

  7. Jan 2017 — Feb 2017 [monthly]

    Active Not Recruiting PHASE3

    First recorded

Dec 1999

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Cancer and Leukemia Group B
  • NCIC Clinical Trials Group
  • NRG Oncology
  • National Cancer Institute (NCI)
  • Radiation Therapy Oncology Group
Data source: Radiation Therapy Oncology Group

For direct contact, visit the study record on ClinicalTrials.gov .