Completed PHASE1 INTERVENTIONAL 1-arm NCT00004604

Biological Therapy in Treating Patients With Metastatic Cancer

A Phase I Study of Active Immunotherapy With Carcinoembryonic Antigen RNA-Pulsed, Autologous Human Cultured Dendritic Cells in Patients With Metastatic Malignancies Expressing Carcinoembryonic Antigen

Sponsor: Duke University

Conditions Breast Cancer Colorectal Cancer Extrahepatic Bile Duct Cancer Gallbladder Cancer Gastric Cancer Head and Neck Cancer Liver Cancer Lung Cancer Metastatic Cancer Ovarian Cancer Pancreatic Cancer Testicular Germ Cell Tumor

Interventions CEA RNA-pulsed DC cancer vaccine

Updated 6 times since 2017 Last updated: Feb 21, 2013 Started: Feb 28, 1997 Primary completion: Jun 30, 2001 Completion: Jul 31, 2002

This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Listed as NCT00004604, this PHASE1 trial focuses on Breast Cancer and Colorectal Cancer and remains completed. Sponsored by Duke University, it has been updated 6 times since 1997, reflecting limited change activity. This study contributes to the evolving evidence base for cancer treatment protocols.

Status Flow

Change History

6 versions recorded

Sep 2024 — Present [monthly]

Completed PHASE1
Jul 2024 — Sep 2024 [monthly]

Completed PHASE1
Jan 2021 — Jul 2024 [monthly]

Completed PHASE1
Jun 2018 — Jan 2021 [monthly]

Completed PHASE1
Feb 2017 — Jun 2018 [monthly]

Completed PHASE1

▶ Show 1 earlier version

Jan 2017 — Feb 2017 [monthly]

Completed PHASE1

First recorded

Feb 1997

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:

Duke University
National Cancer Institute (NCI)

Data source: Duke University

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations

• Durham, United States