deltatrials
Completed PHASE2 INTERVENTIONAL 1-arm NCT00006436

EPOCH and Rituximab to Treat Non-Hodgkin's Lymphoma in Patients With HIV Infection

Short-Course EPOCH - Rituximab in Untreated CD-20+ HIV-Associated Lymphomas

Sponsor: National Cancer Institute (NCI)

Conditions Lymphoma, AIDS-related Lymphoma, Large B-Cell, Diffuse
Interventions EPOCH Filgrastim Rituximab
Updated 46 times since 2017 Last updated: Dec 15, 2025 Started: Jan 29, 2001 Primary completion: Nov 30, 2020 Completion: Jan 18, 2024
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

A PHASE2 clinical study on Lymphoma, AIDS-related and Lymphoma, Large B-Cell, Diffuse, this trial is completed. The trial is conducted by National Cancer Institute (NCI) and has accumulated 46 data snapshots since 2001. Oncology trials at this stage typically focus on safety, tolerability, and early efficacy signals.

Status Flow

~Jan 2017 – ~Feb 2017 · 31 days · monthly snapshot~Feb 2017 – ~Jun 2018 · 16 months · monthly snapshot~Jun 2018 – ~Sep 2018 · 3 months · monthly snapshot~Sep 2018 – ~Oct 2018 · 30 days · monthly snapshot~Oct 2018 – ~Nov 2018 · 31 days · monthly snapshot~Nov 2018 – ~Jan 2019 · 2 months · monthly snapshot~Jan 2019 – ~Feb 2019 · 31 days · monthly snapshot~Feb 2019 – ~Mar 2019 · 28 days · monthly snapshot~Mar 2019 – ~Apr 2019 · 31 days · monthly snapshot~Apr 2019 – ~May 2019 · 30 days · monthly snapshot~May 2019 – ~Jun 2019 · 31 days · monthly snapshot~Jun 2019 – ~Jul 2019 · 30 days · monthly snapshot~Jul 2019 – ~Aug 2019 · 31 days · monthly snapshot~Aug 2019 – ~Sep 2019 · 31 days · monthly snapshot~Sep 2019 – ~Nov 2019 · 2 months · monthly snapshot~Nov 2019 – ~Dec 2019 · 30 days · monthly snapshot~Dec 2019 – ~Feb 2020 · 2 months · monthly snapshot~Feb 2020 – ~Mar 2020 · 29 days · monthly snapshot~Mar 2020 – ~Apr 2020 · 31 days · monthly snapshot~Apr 2020 – ~May 2020 · 30 days · monthly snapshot~May 2020 – ~Jun 2020 · 31 days · monthly snapshot~Jun 2020 – ~Jul 2020 · 30 days · monthly snapshot~Jul 2020 – ~Aug 2020 · 31 days · monthly snapshot~Aug 2020 – ~Sep 2020 · 31 days · monthly snapshot~Sep 2020 – ~Oct 2020 · 30 days · monthly snapshot~Oct 2020 – ~Nov 2020 · 31 days · monthly snapshot~Nov 2020 – ~Dec 2020 · 30 days · monthly snapshot~Dec 2020 – ~Jan 2021 · 31 days · monthly snapshot~Jan 2021 – ~Mar 2021 · 59 days · monthly snapshot~Mar 2021 – ~Apr 2021 · 31 days · monthly snapshot~Apr 2021 – ~May 2021 · 30 days · monthly snapshot~May 2021 – ~Jun 2021 · 31 days · monthly snapshot~Jun 2021 – ~Sep 2021 · 3 months · monthly snapshot~Sep 2021 – ~Oct 2021 · 30 days · monthly snapshot~Oct 2021 – ~Feb 2022 · 4 months · monthly snapshot~Feb 2022 – ~Mar 2022 · 28 days · monthly snapshot~Mar 2022 – ~Apr 2022 · 31 days · monthly snapshot~Apr 2022 – ~Jul 2022 · 3 months · monthly snapshot~Jul 2022 – ~Sep 2022 · 2 months · monthly snapshot~Sep 2022 – ~Sep 2023 · 12 months · monthly snapshot~Sep 2023 – ~Jul 2024 · 10 months · monthly snapshot~Jul 2024 – ~Aug 2024 · 31 days · monthly snapshot~Aug 2024 – ~Sep 2024 · 31 days · monthly snapshot~Sep 2024 – ~Oct 2024 · 30 days · monthly snapshot~Oct 2024 – ~Jan 2026 · 15 months · monthly snapshot~Jan 2026 – present · 8 months · monthly snapshot

Change History

46 versions recorded

  1. Jan 2026 — Present [monthly]

    Completed PHASE2

  2. Oct 2024 — Jan 2026 [monthly]

    Completed PHASE2

    Status: Active Not Recruiting → Completed

  3. Sep 2024 — Oct 2024 [monthly]

    Active Not Recruiting PHASE2

  4. Aug 2024 — Sep 2024 [monthly]

    Active Not Recruiting PHASE2

  5. Jul 2024 — Aug 2024 [monthly]

    Active Not Recruiting PHASE2

▶ Show 41 earlier versions

  1. Sep 2023 — Jul 2024 [monthly]

    Active Not Recruiting PHASE2

  2. Sep 2022 — Sep 2023 [monthly]

    Active Not Recruiting PHASE2

  3. Jul 2022 — Sep 2022 [monthly]

    Active Not Recruiting PHASE2

  4. Apr 2022 — Jul 2022 [monthly]

    Active Not Recruiting PHASE2

  5. Mar 2022 — Apr 2022 [monthly]

    Active Not Recruiting PHASE2

  6. Feb 2022 — Mar 2022 [monthly]

    Active Not Recruiting PHASE2

  7. Oct 2021 — Feb 2022 [monthly]

    Active Not Recruiting PHASE2

  8. Sep 2021 — Oct 2021 [monthly]

    Active Not Recruiting PHASE2

  9. Jun 2021 — Sep 2021 [monthly]

    Active Not Recruiting PHASE2

  10. May 2021 — Jun 2021 [monthly]

    Active Not Recruiting PHASE2

  11. Apr 2021 — May 2021 [monthly]

    Active Not Recruiting PHASE2

  12. Mar 2021 — Apr 2021 [monthly]

    Active Not Recruiting PHASE2

    Status: Recruiting → Active Not Recruiting

  13. Jan 2021 — Mar 2021 [monthly]

    Recruiting PHASE2

  14. Dec 2020 — Jan 2021 [monthly]

    Recruiting PHASE2

  15. Nov 2020 — Dec 2020 [monthly]

    Recruiting PHASE2

  16. Oct 2020 — Nov 2020 [monthly]

    Recruiting PHASE2

  17. Sep 2020 — Oct 2020 [monthly]

    Recruiting PHASE2

  18. Aug 2020 — Sep 2020 [monthly]

    Recruiting PHASE2

  19. Jul 2020 — Aug 2020 [monthly]

    Recruiting PHASE2

  20. Jun 2020 — Jul 2020 [monthly]

    Recruiting PHASE2

  21. May 2020 — Jun 2020 [monthly]

    Recruiting PHASE2

  22. Apr 2020 — May 2020 [monthly]

    Recruiting PHASE2

  23. Mar 2020 — Apr 2020 [monthly]

    Recruiting PHASE2

  24. Feb 2020 — Mar 2020 [monthly]

    Recruiting PHASE2

  25. Dec 2019 — Feb 2020 [monthly]

    Recruiting PHASE2

  26. Nov 2019 — Dec 2019 [monthly]

    Recruiting PHASE2

  27. Sep 2019 — Nov 2019 [monthly]

    Recruiting PHASE2

  28. Aug 2019 — Sep 2019 [monthly]

    Recruiting PHASE2

  29. Jul 2019 — Aug 2019 [monthly]

    Recruiting PHASE2

  30. Jun 2019 — Jul 2019 [monthly]

    Recruiting PHASE2

  31. May 2019 — Jun 2019 [monthly]

    Recruiting PHASE2

  32. Apr 2019 — May 2019 [monthly]

    Recruiting PHASE2

  33. Mar 2019 — Apr 2019 [monthly]

    Recruiting PHASE2

  34. Feb 2019 — Mar 2019 [monthly]

    Recruiting PHASE2

  35. Jan 2019 — Feb 2019 [monthly]

    Recruiting PHASE2

  36. Nov 2018 — Jan 2019 [monthly]

    Recruiting PHASE2

  37. Oct 2018 — Nov 2018 [monthly]

    Recruiting PHASE2

  38. Sep 2018 — Oct 2018 [monthly]

    Recruiting PHASE2

  39. Jun 2018 — Sep 2018 [monthly]

    Recruiting PHASE2

  40. Feb 2017 — Jun 2018 [monthly]

    Recruiting PHASE2

    Status: Suspended → Recruiting

  41. Jan 2017 — Feb 2017 [monthly]

    Suspended PHASE2

    First recorded

Jan 2001

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • National Cancer Institute (NCI)
Data source: National Institutes of Health Clinical Center (CC)

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations