deltatrials
Completed PHASE3 NCT00021255

Combination Chemotherapy With or Without Trastuzumab in Treating Women With Breast Cancer

Multicenter Phase III Randomized Trial Comparing Doxorubicin and Cyclophosphamide Followed By Docetaxel (AC-T) With Doxorubicin and Cyclophosphamide Followed By Docetaxel and Trastuzumab (Herceptin)(AC-TH) and With Docetaxel, Carboplatin and Trastuzumab (TCH) In The Adjuvant Treatment Of Node Positive and High Risk Node Negative Patients With Operable Breast Cancer Containing The HER2 Alteration

Sponsor: Cancer International Research Group (CIRG)

Updated 7 times since 2017 Last updated: Sep 26, 2016 Started: Apr 30, 2001 Primary completion: Dec 31, 2014 Completion: Dec 31, 2014

This PHASE3 trial investigates Breast Neoplasms and is currently completed. Cancer International Research Group (CIRG) leads this study, which shows 7 recorded versions since 2001 — indicating limited longitudinal coverage. As an oncology study, it adds to the longitudinal record of treatment development for this indication.

Change History

7 versions recorded
  1. Sep 2025 — Present [monthly]

    Completed PHASE3

  2. Sep 2024 — Sep 2025 [monthly]

    Completed PHASE3

  3. Jul 2024 — Sep 2024 [monthly]

    Completed PHASE3

  4. Jan 2021 — Jul 2024 [monthly]

    Completed PHASE3

  5. Jun 2018 — Jan 2021 [monthly]

    Completed PHASE3

Show 2 earlier versions
  1. Feb 2017 — Jun 2018 [monthly]

    Completed PHASE3

  2. Jan 2017 — Feb 2017 [monthly]

    Completed PHASE3

    First recorded

Apr 2001

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Cancer International Research Group (CIRG)
  • Sanofi
Data source: Sanofi

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations

Barcelona, Spain, Beirut, Lebanon, Bogotá, Colombia, Bratislava, Slovakia, Bridgewater, United States, Bromma, Sweden, Bucharest, Romania, Budapest, Hungary, Buenos Aires, Argentina, Cairo, Egypt and 32 more location s