deltatrials
Completed PHASE3 INTERVENTIONAL 2-arm NCT00033293

Cyclophosphamide and Prednisone With or Without Immunoglobulin in Treating Abnormal Muscle Movement in Children With Neuroblastoma

A Phase III Randomized Trial of Intravenous Gammaglobulin Therapy for Patients With Neuroblastoma Associated Opsoclonus-Myoclonus-Ataxia Syndrome Treated With Chemotherapy and Prednisone

Sponsor: Children's Oncology Group

Updated 13 times since 2017 Last updated: Mar 22, 2023 Started: Mar 15, 2004 Primary completion: Dec 10, 2013 Completion: Dec 31, 2022
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Listed as NCT00033293, this PHASE3 trial focuses on Localized Resectable Neuroblastoma and Localized Unresectable Neuroblastoma and remains completed. Sponsored by Children's Oncology Group, it has been updated 13 times since 2004, reflecting substantial change activity. This study adds to the evidence base for this therapeutic area through structured, versioned documentation.

Status Flow

~Jan 2017 – ~Feb 2017 · 31 days · monthly snapshot~Feb 2017 – ~Jul 2017 · 5 months · monthly snapshot~Jul 2017 – ~Jun 2018 · 11 months · monthly snapshot~Jun 2018 – ~Apr 2020 · 22 months · monthly snapshot~Apr 2020 – ~Nov 2020 · 7 months · monthly snapshot~Nov 2020 – ~Jan 2021 · 2 months · monthly snapshot~Jan 2021 – ~Feb 2022 · 13 months · monthly snapshot~Feb 2022 – ~Feb 2023 · 12 months · monthly snapshot~Feb 2023 – ~May 2023 · 3 months · monthly snapshot~May 2023 – ~Jul 2024 · 14 months · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – ~Sep 2025 · 12 months · monthly snapshot~Sep 2025 – present · 11 months · monthly snapshot

Change History

13 versions recorded
  1. Sep 2025 — Present [monthly]

    Completed PHASE3

  2. Sep 2024 — Sep 2025 [monthly]

    Completed PHASE3

  3. Jul 2024 — Sep 2024 [monthly]

    Completed PHASE3

  4. May 2023 — Jul 2024 [monthly]

    Completed PHASE3

  5. Feb 2023 — May 2023 [monthly]

    Completed PHASE3

    Status: Active Not RecruitingCompleted

Show 8 earlier versions
  1. Feb 2022 — Feb 2023 [monthly]

    Active Not Recruiting PHASE3

    Status: Unknown StatusActive Not Recruiting

  2. Jan 2021 — Feb 2022 [monthly]

    Unknown Status PHASE3

  3. Nov 2020 — Jan 2021 [monthly]

    Unknown Status PHASE3

  4. Apr 2020 — Nov 2020 [monthly]

    Unknown Status PHASE3

    Status: CompletedUnknown Status

  5. Jun 2018 — Apr 2020 [monthly]

    Completed PHASE3

  6. Jul 2017 — Jun 2018 [monthly]

    Completed PHASE3

  7. Feb 2017 — Jul 2017 [monthly]

    Completed PHASE3

  8. Jan 2017 — Feb 2017 [monthly]

    Completed PHASE3

    First recorded

Mar 2004

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Children's Oncology Group
  • National Cancer Institute (NCI)
Data source: Children's Oncology Group

For direct contact, visit the study record on ClinicalTrials.gov .