Completed PHASE2 INTERVENTIONAL 3-arm NCT00040677

A Study of the Efficacy and Safety of ICA-17043 (With or Without Hydroxyurea) in Patients With Sickle Cell Anemia.

A Phase II, Multicenter, Twelve-Week, Randomized, Double-Blind, Placebo-Controlled, Parallel-Group, Dose-Range-Finding Study of the Efficacy and Safety of ICA-17043 With or Without Hydroxyurea Therapy in Patients With Sickle Cell Anemia

Sponsor: Icagen

Conditions Sickle Cell Anemia Sickle Cell Disease

Interventions High dose ICA-17043 Low Dose ICA-17043 Placebo

Updated 8 times since 2017 Last updated: Jul 13, 2011 Started: Feb 28, 2002 Primary completion: Nov 30, 2003 Completion: Jan 31, 2004

This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

This PHASE2 trial investigates Sickle Cell Anemia and Sickle Cell Disease and is currently completed. Icagen leads this study, which shows 8 recorded versions since 2002 — indicating limited longitudinal coverage. The change history captured here reflects the iterative nature of clinical trial conduct.

Status Flow

Change History

8 versions recorded

Sep 2025 — Present [monthly]

Completed PHASE2
Sep 2024 — Sep 2025 [monthly]

Completed PHASE2
Jul 2024 — Sep 2024 [monthly]

Completed PHASE2
Apr 2022 — Jul 2024 [monthly]

Completed PHASE2
Jan 2021 — Apr 2022 [monthly]

Completed PHASE2

▶ Show 3 earlier versions

Jun 2018 — Jan 2021 [monthly]

Completed PHASE2
Feb 2017 — Jun 2018 [monthly]

Completed PHASE2
Jan 2017 — Feb 2017 [monthly]

Completed PHASE2

First recorded

Feb 2002

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:

Icagen

Data source: Icagen

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations

Augusta, United States , Baltimore, United States , Birmingham, United States , Boston, United States , Brooklyn, United States , Chapel Hill, United States , Chicago, United States , Detroit, United States , Durham, United States , Houston, United States and 9 more locations