Completed PHASE2 INTERVENTIONAL 8-arm NCT00044694

Evaluation of the Effect on Glucose Control and the Safety and Tolerability of AC2993 in Patients With Type 2 Diabetes Mellitus

A Phase 2, Randomized, Triple-Blind, Placebo-Controlled, Short-Term, Dose-Response Study to Examine the Effect on Glucose Control and Safety and Tolerability of AC2993 Given Two Times a Day in Subjects With Type 2 Diabetes Mellitus

Sponsor: AstraZeneca

Conditions Diabetes Mellitus, Non-Insulin-Dependent

Interventions AC2993 10.0 mcg AC2993 2.5 mcg AC2993 5.0 mcg AC2993 7.5 mcg Placebo 0.01 mL Placebo 0.02 mL Placebo 0.03 mL Placebo 0.04 mL

Updated 7 times since 2017 Last updated: Feb 19, 2015 Started: Aug 31, 2002 Primary completion: May 31, 2003 Completion: May 31, 2003

This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

This PHASE2 trial investigates Diabetes Mellitus, Non-Insulin-Dependent and is currently completed. AstraZeneca leads this study, which shows 7 recorded versions since 2002 — indicating limited longitudinal coverage. The change history captured here reflects the iterative nature of clinical trial conduct.

Status Flow

Change History

7 versions recorded

Sep 2025 — Present [monthly]

Completed PHASE2
Sep 2024 — Sep 2025 [monthly]

Completed PHASE2
Jul 2024 — Sep 2024 [monthly]

Completed PHASE2
Jan 2021 — Jul 2024 [monthly]

Completed PHASE2
Jun 2018 — Jan 2021 [monthly]

Completed PHASE2

▶ Show 2 earlier versions

Feb 2017 — Jun 2018 [monthly]

Completed PHASE2
Jan 2017 — Feb 2017 [monthly]

Completed PHASE2

First recorded

Aug 2002

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:

AstraZeneca

Data source: AstraZeneca

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations

Anaheim, United States , Aurora, United States , Bellflower, United States , Benbrook, United States , Birmingham, United States , Blairsville, United States , Boise, United States , Cary, United States , Chicago, United States , Chula Vista, United States and 21 more locations