deltatrials
Completed PHASE2 INTERVENTIONAL 1-arm NCT00045305

Reduced-Intensity Regimen Before Donor Bone Marrow Transplant in Treating Patients With Myelodysplastic Syndromes

A Phase II Study of Reduced Intensity Allogeneic Bone Marrow Transplant for the Treatment of Myelodysplastic Syndromes

Sponsor: Eastern Cooperative Oncology Group

Conditions Leukemia Myelodysplastic Syndromes Myelodysplastic/Myeloproliferative Neoplasms
Interventions Cyclosporine Methotrexate Mycofenolate mofetil Pentostatin Photopheresis Total body irradiation allogeneic bone marrow peripheral blood stem cell
Updated 7 times since 2017 Last updated: Jun 13, 2023 Started: Oct 24, 2006 Primary completion: Feb 28, 2014 Completion: Sep 30, 2014
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Listed as NCT00045305, this PHASE2 trial focuses on Leukemia and Myelodysplastic Syndromes and remains completed. Sponsored by Eastern Cooperative Oncology Group, it has been updated 7 times since 2006, reflecting limited change activity. This study contributes to the evolving evidence base for cancer treatment protocols.

Status Flow

~Jan 2017 – ~Feb 2017 · 31 days · monthly snapshotCompleted~Feb 2017 – ~Jun 2018 · 16 months · monthly snapshotCompleted~Jun 2018 – ~Jan 2021 · 31 months · monthly snapshotCompleted~Jan 2021 – ~Jul 2023 · 30 months · monthly snapshotCompleted~Jul 2023 – ~Jul 2024 · 12 months · monthly snapshotCompleted~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshotCompleted~Sep 2024 – present · 22 months · monthly snapshotCompleted

Change History

7 versions recorded

  1. Sep 2024 — Present [monthly]

    Completed PHASE2

  2. Jul 2024 — Sep 2024 [monthly]

    Completed PHASE2

  3. Jul 2023 — Jul 2024 [monthly]

    Completed PHASE2

  4. Jan 2021 — Jul 2023 [monthly]

    Completed PHASE2

  5. Jun 2018 — Jan 2021 [monthly]

    Completed PHASE2

▶ Show 2 earlier versions

  1. Feb 2017 — Jun 2018 [monthly]

    Completed PHASE2

  2. Jan 2017 — Feb 2017 [monthly]

    Completed PHASE2

    First recorded

Oct 2006

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Eastern Cooperative Oncology Group
  • National Cancer Institute (NCI)
Data source: Eastern Cooperative Oncology Group

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations