deltatrials
Completed PHASE3 NCT00048295

Alicaforsen (ISIS 2302) in Patients With Active Crohn's Disease

ISIS 2302-CS21, Phase 3 Double-Masked, Placebo-Controlled Study of Alicaforsen (ISIS 2302), an Antisense Inhibitor of ICAM-1, for the Treatment of Patients With Active Crohn's Disease

Sponsor: Ionis Pharmaceuticals, Inc.

Interventions Alicaforsen
Updated 8 times since 2017 Last updated: Aug 11, 2022 Started: May 31, 2002

A PHASE3 clinical study on Crohn's Disease, this trial is completed. The trial is conducted by Ionis Pharmaceuticals, Inc. and has accumulated 8 data snapshots since 2002. Longitudinal tracking of this trial contributes to a broader understanding of treatment development timelines.

Status Flow

~Jan 2017 – ~Jun 2018 · 17 months · monthly snapshotUnknown Status~Jun 2018 – ~Sep 2020 · 27 months · monthly snapshotUnknown Status~Sep 2020 – ~Jan 2021 · 4 months · monthly snapshotUnknown Status~Jan 2021 – ~Sep 2022 · 20 months · monthly snapshotUnknown Status~Sep 2022 – ~Jul 2024 · 22 months · monthly snapshotCompleted~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshotCompleted~Sep 2024 – ~Sep 2025 · 12 months · monthly snapshotCompleted~Sep 2025 – present · 7 months · monthly snapshotCompleted

Change History

8 versions recorded
  1. Sep 2025 — Present [monthly]

    Completed PHASE3

  2. Sep 2024 — Sep 2025 [monthly]

    Completed PHASE3

  3. Jul 2024 — Sep 2024 [monthly]

    Completed PHASE3

  4. Sep 2022 — Jul 2024 [monthly]

    Completed PHASE3

    Status: Unknown StatusCompleted

  5. Jan 2021 — Sep 2022 [monthly]

    Unknown Status PHASE3

Show 3 earlier versions
  1. Sep 2020 — Jan 2021 [monthly]

    Unknown Status PHASE3

  2. Jun 2018 — Sep 2020 [monthly]

    Unknown Status PHASE3

  3. Jan 2017 — Jun 2018 [monthly]

    Unknown Status PHASE3

    First recorded

May 2002

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Ionis Pharmaceuticals, Inc.
Data source: Ionis Pharmaceuticals, Inc.

For direct contact, visit the study record on ClinicalTrials.gov .