Completed NA INTERVENTIONAL 4-arm NCT00050089

CSP #512 - Options in Management With Anti-Retrovirals (OPTIMA)

CSP #512 - Options in Management With Anti-Retrovirals (OPTIMA), Management of Patients With HIV Infection for Whom First and Second-line Highly Active Anti-Retroviral Therapy Has Failed

Sponsor: Canadian Institutes of Health Research (CIHR)

Conditions AIDS HIV Infections

Interventions No Antiretroviral Drug-Free Period (No ARDFP) vs ARDFP Standard ART vs Mega ART

Updated 9 times since 2017 Last updated: Apr 3, 2015 Started: Jan 31, 2001 Primary completion: Dec 31, 2007 Completion: Dec 31, 2007

This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

A NA clinical study on AIDS and HIV Infections, this trial is completed. The trial is conducted by Canadian Institutes of Health Research (CIHR) and has accumulated 9 data snapshots since 2001. Infectious disease trials contribute critical data for public health response and treatment development.

Status Flow

Change History

9 versions recorded

Sep 2025 — Present [monthly]

Completed NA
Sep 2024 — Sep 2025 [monthly]

Completed NA
Jul 2024 — Sep 2024 [monthly]

Completed NA
Jan 2023 — Jul 2024 [monthly]

Completed NA
Dec 2022 — Jan 2023 [monthly]

Completed NA

▶ Show 4 earlier versions

Jan 2021 — Dec 2022 [monthly]

Completed NA
Aug 2018 — Jan 2021 [monthly]

Completed NA
Jun 2018 — Aug 2018 [monthly]

Completed NA
Jan 2017 — Jun 2018 [monthly]

Completed NA

First recorded

Jan 2001

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:

Canadian Institutes of Health Research (CIHR)
Medical Research Council
US Department of Veterans Affairs

Data source: VA Office of Research and Development

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations

Ann Arbor, United States , Baltimore, United States , Boston, United States , Chicago, United States , Cincinnati, United States , Cleveland, United States , Columbia, United States , Dallas, United States , Decatur, United States , Durham, United States and 20 more locations