Completed PHASE2 INTERVENTIONAL 2-arm NCT00057837

Comparison of Two Combination Chemotherapy Regimens in Treating Patients With Extensive-Stage Small Cell Lung Cancer

A Randomized Phase II Study: Sequencing Topoisomerase Inhibitors for Extensive Stage Small Cell Lung Cancer (SCLC): Topotecan Sequenced With Etoposide/Cisplatin, and Irinotecan/Cisplatin Sequenced With Etoposide

Sponsor: Eastern Cooperative Oncology Group

Conditions Extensive Stage Small Cell Lung Cancer

Interventions Cisplatin Etoposide G-CSF Irinotecan Topotecan

Updated 8 times since 2017 Last updated: Jun 20, 2023 Started: Jul 14, 2004 Primary completion: Jan 31, 2012 Completion: Aug 31, 2012

This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

This PHASE2 trial investigates Extensive Stage Small Cell Lung Cancer and is currently completed. Eastern Cooperative Oncology Group leads this study, which shows 8 recorded versions since 2004 — indicating limited longitudinal coverage. As an oncology study, it adds to the longitudinal record of treatment development for this indication.

Status Flow

Change History

8 versions recorded

Sep 2025 — Present [monthly]

Completed PHASE2
Sep 2024 — Sep 2025 [monthly]

Completed PHASE2
Jul 2024 — Sep 2024 [monthly]

Completed PHASE2
Aug 2023 — Jul 2024 [monthly]

Completed PHASE2
Jan 2021 — Aug 2023 [monthly]

Completed PHASE2

▶ Show 3 earlier versions

Jun 2018 — Jan 2021 [monthly]

Completed PHASE2
Feb 2017 — Jun 2018 [monthly]

Completed PHASE2
Jan 2017 — Feb 2017 [monthly]

Completed PHASE2

First recorded

Jul 2004

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:

Eastern Cooperative Oncology Group
National Cancer Institute (NCI)

Data source: Eastern Cooperative Oncology Group

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations

Akron, United States , Aurora, United States , Baltimore, United States , Bettendorf, United States , Bryn Mawr, United States , Chanute, United States , Cleveland, United States , Dodge City, United States , East Stroudsburg, United States , Eau Claire, United States and 52 more locations