Completed PHASE3 INTERVENTIONAL 2-arm NCT00070148

Oxandrolone Compared With Megestrol in Preventing Weight Loss in Patients Receiving Chemotherapy for Cancer

A Phase III Randomized Study Comparing The Effects Of Oxandrolone (Oxandrin) And Megestrol Acetate (Megace) On Lean Body Mass, Weight, Body Fat, And Quality Of Life In Patients With Solid Tumors And Weight Loss Receiving Chemotherapy

Sponsor: National Cancer Institute (NCI)

Conditions Unspecified Adult Solid Tumor, Protocol Specific Weight Changes

Interventions Megestrol Acetate Oxandrolone 20 mg

Updated 9 times since 2017 Last updated: Sep 7, 2021 Started: Mar 1, 2004 Primary completion: Aug 1, 2007 Completion: Aug 1, 2007

This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Listed as NCT00070148, this PHASE3 trial focuses on Unspecified Adult Solid Tumor, Protocol Specific and Weight Changes and remains completed. Sponsored by National Cancer Institute (NCI), it has been updated 9 times since 2004, reflecting limited change activity. This study contributes to the evolving evidence base for cancer treatment protocols.

Status Flow

Change History

9 versions recorded

Sep 2024 — Present [monthly]

Completed PHASE3
Jul 2024 — Sep 2024 [monthly]

Completed PHASE3
Oct 2021 — Jul 2024 [monthly]

Completed PHASE3
Jan 2021 — Oct 2021 [monthly]

Completed PHASE3
Sep 2018 — Jan 2021 [monthly]

Completed PHASE3

▶ Show 4 earlier versions

Jul 2018 — Sep 2018 [monthly]

Completed PHASE3
Jun 2018 — Jul 2018 [monthly]

Completed PHASE3
Feb 2017 — Jun 2018 [monthly]

Completed PHASE3
Jan 2017 — Feb 2017 [monthly]

Completed PHASE3

First recorded

Mar 2004

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:

National Cancer Institute (NCI)
Wake Forest University Health Sciences

Data source: Wake Forest University Health Sciences

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations

Asheville, United States , Baton Rouge, United States , Burlington, United States , Charlotte, United States , Columbus, United States , Danville, United States , Goldsboro, United States , Greensboro, United States , Greenville, United States , Hendersonville, United States and 8 more locations