Dexamethasone Compared With Prednisone During Induction Therapy and Methotrexate With or Without Leucovorin During Maintenance Therapy in Treating Patients With Newly Diagnosed High-Risk Acute Lymphoblastic Leukemia
High Risk B-Precursor Acute Lymphoblastic Leukemia (ALL)
Sponsor: Children's Oncology Group
Listed as NCT00075725, this PHASE3 trial focuses on Acute Lymphoblastic Leukemia and Adult B Acute Lymphoblastic Leukemia and remains completed. Sponsored by Children's Oncology Group, it has been updated 14 times since 2003, reflecting substantial change activity. This study contributes to the evolving evidence base for cancer treatment protocols.
Status Flow
Change History
14 versions recorded-
Sep 2025 — Present [monthly]
Completed PHASE3
-
Sep 2024 — Sep 2025 [monthly]
Completed PHASE3
-
Jul 2024 — Sep 2024 [monthly]
Completed PHASE3
-
Dec 2021 — Jul 2024 [monthly]
Completed PHASE3
-
May 2021 — Dec 2021 [monthly]
Completed PHASE3
Status: Active Not Recruiting → Completed
▶ Show 9 earlier versions
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Apr 2021 — May 2021 [monthly]
Active Not Recruiting PHASE3
Status: Unknown Status → Active Not Recruiting
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Jan 2021 — Apr 2021 [monthly]
Unknown Status PHASE3
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Sep 2020 — Jan 2021 [monthly]
Unknown Status PHASE3
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Apr 2020 — Sep 2020 [monthly]
Unknown Status PHASE3
Status: Completed → Unknown Status
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Oct 2019 — Apr 2020 [monthly]
Completed PHASE3
-
Jun 2018 — Oct 2019 [monthly]
Completed PHASE3
-
May 2017 — Jun 2018 [monthly]
Completed PHASE3
Status: Active Not Recruiting → Completed
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Feb 2017 — May 2017 [monthly]
Active Not Recruiting PHASE3
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Jan 2017 — Feb 2017 [monthly]
Active Not Recruiting PHASE3
First recorded
Dec 2003
Trial started
Per CT.gov start date — pre-dates our first snapshot
Eligibility Summary
No eligibility information available.
Contact Information
- Children's Oncology Group
- National Cancer Institute (NCI)
For direct contact, visit the study record on ClinicalTrials.gov .