Completed PHASE4 INTERVENTIONAL 2-arm NCT00131846

Diuretics In the Management of Essential Hypertension (DIME) Study

Effect of Low Dose Thiazide Diuretics on New Onset Type 2 Diabetes in Patients With Essential Hypertension

Sponsor: Kyoto University

Interventions No diuretics Thiazide diuretics

Updated 8 times since 2017 Last updated: Jun 12, 2024 Started: Apr 30, 2004 Primary completion: Aug 31, 2012 Completion: Nov 30, 2013

This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Listed as NCT00131846, this PHASE4 trial focuses on Hypertension and remains completed. Sponsored by Kyoto University, it has been updated 8 times since 2004, reflecting limited change activity. This study contributes longitudinal data to the cardiovascular research landscape.

Status Flow

Change History

8 versions recorded

Sep 2025 — Present [monthly]

Completed PHASE4
Sep 2024 — Sep 2025 [monthly]

Completed PHASE4
Jul 2024 — Sep 2024 [monthly]

Completed PHASE4
Jun 2023 — Jul 2024 [monthly]

Completed PHASE4
Jan 2021 — Jun 2023 [monthly]

Completed PHASE4

▶ Show 3 earlier versions

Jun 2018 — Jan 2021 [monthly]

Completed PHASE4
Apr 2017 — Jun 2018 [monthly]

Completed PHASE4

Status: Unknown Status → Completed
Jan 2017 — Apr 2017 [monthly]

Unknown Status PHASE4

First recorded

Apr 2004

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:

Kyoto University
University of the Ryukyus

Data source: Kyoto University

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations

• Nishihara, Japan