Completed PHASE4 INTERVENTIONAL 2-arm NCT00135356

Study of Reyataz in HIV-infected Patients With Lipodystrophy Syndrome

A Phase IV, Open-Label, Randomized, Multicenter Trial Assessing a Reyataz-Based Substitution Approach in the Management of Lipodystrophy Syndrome. Research Into Atazanavir in Lipodystrophy (The REAL Study)

Sponsor: Bristol-Myers Squibb

Conditions HIV-Associated Lipodystrophy Syndrome

Interventions Atazanavir (ATV) + ritonavir (RTV), continuation of backbone 2 nucleoside reverse transcriptase inhibitor (NRTIs) continuation of current HAART (boosted protease inhibitor [PI] combination + 2 NRTIs)

Updated 7 times since 2017 Last updated: Apr 20, 2010 Started: Jul 31, 2005 Primary completion: Jul 31, 2007 Completion: Jun 30, 2008

This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Listed as NCT00135356, this PHASE4 trial focuses on HIV-Associated Lipodystrophy Syndrome and remains completed. Sponsored by Bristol-Myers Squibb, it has been updated 7 times since 2005, reflecting limited change activity. This study is part of the global effort to build evidence for infectious disease interventions.

Status Flow

Change History

7 versions recorded

Sep 2025 — Present [monthly]

Completed PHASE4
Sep 2024 — Sep 2025 [monthly]

Completed PHASE4
Jul 2024 — Sep 2024 [monthly]

Completed PHASE4
Jan 2021 — Jul 2024 [monthly]

Completed PHASE4
Jun 2018 — Jan 2021 [monthly]

Completed PHASE4

▶ Show 2 earlier versions

Feb 2017 — Jun 2018 [monthly]

Completed PHASE4
Jan 2017 — Feb 2017 [monthly]

Completed PHASE4

First recorded

Jul 2005

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:

Bristol-Myers Squibb

Data source: Bristol-Myers Squibb

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations

Barcelona, Spain , Bondy, France , Brescia, Italy , Brighton, United Kingdom , Elche (Alicante), Spain , Fort Lauderdale, United States , Frankfurt am Main, Germany , Guadalajara, Mexico , Guipuzcoa, Spain , Honolulu, United States and 20 more locations