Completed PHASE2 INTERVENTIONAL 4-arm NCT00135668

Dose-response Study of Sodium Nitroprusside in Children Requiring Controlled Hypotension in the Operating Room

A Phase 2 Multicenter, Randomized, Double-blind, Parallel Group, Dose-ranging, Effect-controlled Study to Determine the Pharmacokinetics and Pharmacodynamics of Sodium Nitroprusside in Pediatric Subjects

Sponsor: Duke University

Conditions Hypotension

Interventions Nitroprusside

Updated 7 times since 2017 Last updated: Dec 12, 2023 Started: Aug 31, 2005 Primary completion: Mar 31, 2008 Completion: Feb 28, 2009

This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Listed as NCT00135668, this PHASE2 trial focuses on Hypotension and remains completed. Sponsored by Duke University, it has been updated 7 times since 2005, reflecting limited change activity. This study adds to the evidence base for this therapeutic area through structured, versioned documentation.

Status Flow

Change History

7 versions recorded

Sep 2024 — Present [monthly]

Completed PHASE2
Jul 2024 — Sep 2024 [monthly]

Completed PHASE2
Feb 2024 — Jul 2024 [monthly]

Completed PHASE2
Jan 2021 — Feb 2024 [monthly]

Completed PHASE2
Jun 2018 — Jan 2021 [monthly]

Completed PHASE2

▶ Show 2 earlier versions

Feb 2017 — Jun 2018 [monthly]

Completed PHASE2
Jan 2017 — Feb 2017 [monthly]

Completed PHASE2

First recorded

Aug 2005

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:

Duke University
Stanford University
The Emmes Company, LLC

Data source: The Emmes Company, LLC

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations

• Stanford, United States