Completed NA INTERVENTIONAL 2-arm NCT00139477

Study of Serum Markers for Cardiovascular Risk in Obese Youth and Impact of Lifestyle and Medication Intervention

Understanding the Effects of Therapeutic Intervention on Cardiovascular Risk Markers, Insulin Resistance, and Intra-Hepatic Fat Contents in Obese Children at High Risk for the Metabolic Syndrome.

Sponsor: Nemours Children's Clinic

Conditions Obesity

Interventions Dietary modification with caloric restriction Establishment of exercise protocol Metformin

Updated 8 times since 2017 Last updated: Mar 20, 2023 Started: Nov 30, 2003 Primary completion: May 31, 2009 Completion: Sep 30, 2011

This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

A NA clinical study on Obesity, this trial is completed. The trial is conducted by Nemours Children's Clinic and has accumulated 8 data snapshots since 2003. Longitudinal tracking of this trial contributes to a broader understanding of treatment development timelines.

Status Flow

Change History

8 versions recorded

Jan 2026 — Present [monthly]

Completed NA
Sep 2024 — Present [monthly]

Completed NA
Jul 2024 — Sep 2024 [monthly]

Completed NA
May 2023 — Jul 2024 [monthly]

Completed NA
Dec 2021 — May 2023 [monthly]

Completed NA

▶ Show 3 earlier versions

Jan 2021 — Dec 2021 [monthly]

Completed NA
Jun 2018 — Jan 2021 [monthly]

Completed NA
Jan 2017 — Jun 2018 [monthly]

Completed NA

First recorded

Nov 2003

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:

Nemours Children's Clinic
Thrasher Research Fund

Data source: Nemours Children's Clinic

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations

• Jacksonville, United States