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Completed PHASE4 INTERVENTIONAL 3-arm NCT00159107

Integrative Therapy in Alcoholism

Acamprosate and Integrative Behavior Therapy in the Outpatient Treatment of Alcohol Dependents

Sponsor: German Addiction Research Network

Conditions Alcoholism
Updated 7 times since 2017 Last updated: Jan 29, 2008 Started: May 31, 2003 Completion: Dec 31, 2006
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Listed as NCT00159107, this PHASE4 trial focuses on Alcoholism and remains completed. Sponsored by German Addiction Research Network, it has been updated 7 times since 2003, reflecting limited change activity. This study adds to the evidence base for this therapeutic area through structured, versioned documentation.

Study Description(click to expand)

The objective of this multi-center study is to optimize the long-term treatment of patients with alcohol dependence. This investigation should contribute to the issue of effective relapse prevention. Each treatment condition is lasting 6 months: a) Behavior Group Therapy + Acamprosate, b) Behavior Group Therapy + Placebo and c) support and counseling + Acamprosate. Follow-up examinations carried out 3 and 6 months after the end of treatment.

The objective of this multi-center study is to optimize the long-term treatment of patients with alcohol dependence. This investigation should contribute to the issue of effective relapse prevention. Each treatment condition is lasting 6 months: a) Behavior Group Therapy + Acamprosate, b) Behavior Group Therapy + Placebo and c) support and counseling + Acamprosate. Follow-up examinations carried out 3 and 6 months after the end of treatment.

Status Flow

~Jan 2017 – ~Jun 2018 · 17 months · monthly snapshotCompleted~Jun 2018 – ~Jan 2021 · 31 months · monthly snapshotCompleted~Jan 2021 – ~Jun 2022 · 17 months · monthly snapshotCompleted~Jun 2022 – ~Jul 2024 · 25 months · monthly snapshotCompleted~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshotCompleted~Sep 2024 – present · 19 months · monthly snapshotCompleted~Jan 2026 – present · 3 months · monthly snapshotCompleted

Change History

7 versions recorded
  1. Jan 2026 — Present [monthly]

    Completed PHASE4

  2. Sep 2024 — Present [monthly]

    Completed PHASE4

  3. Jul 2024 — Sep 2024 [monthly]

    Completed PHASE4

  4. Jun 2022 — Jul 2024 [monthly]

    Completed PHASE4

  5. Jan 2021 — Jun 2022 [monthly]

    Completed PHASE4

Show 2 earlier versions
  1. Jun 2018 — Jan 2021 [monthly]

    Completed PHASE4

  2. Jan 2017 — Jun 2018 [monthly]

    Completed PHASE4

    First recorded

May 2003

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • German Addiction Research Network
  • German Federal Ministry of Education and Research
  • Heinrich-Heine University, Duesseldorf
  • Merck Sharp & Dohme LLC
  • Psychosomatic Clinic of Bergisch Gladbach
  • University of Bonn
  • University of Homburg
  • Universität Duisburg-Essen
Data source: Heinrich-Heine University, Duesseldorf

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations