deltatrials
Terminated PHASE3 INTERVENTIONAL NCT00206089

Melagatran/Ximelagatran Versus Enoxaparin for the Prevention of Venous Thromboembolic Events (EXTEND)

The EXTEND Study: A Randomized, Double-blind, Parallel-group, Phase III b, Multi-centre Study Evaluating Extended Prophylactic Treatment With Melagatran/Ximelagatran Versus Enoxaparin for the Prevention of Venous Thromboembolic Events in Patients Undergoing Elective Hip Replacement or Hip Fracture Surgery.

Sponsor: AstraZeneca

Interventions EXANTA
Updated 10 times since 2017 Last updated: Nov 11, 2010 Started: Sep 30, 2005 Primary completion: Aug 31, 2006 Completion: Aug 31, 2006
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Terminated

Melagatran/ximelagatran was withdrawn from the market and clinical development in February 2006 in the interest of patient safety.

A PHASE3 clinical study on Thromboembolism, this trial is terminated or withdrawn. The trial is conducted by AstraZeneca and has accumulated 10 data snapshots since 2005. Longitudinal tracking of this trial contributes to a broader understanding of treatment development timelines.

Status Flow

~Jan 2017 – ~Aug 2017 · 7 months · monthly snapshotTerminated~Aug 2017 – ~May 2018 · 9 months · monthly snapshotTerminated~May 2018 – ~Jun 2018 · 31 days · monthly snapshotTerminated~Jun 2018 – ~Nov 2020 · 29 months · monthly snapshotTerminated~Nov 2020 – ~Jan 2021 · 2 months · monthly snapshotTerminated~Jan 2021 – ~Dec 2021 · 11 months · monthly snapshotTerminated~Dec 2021 – ~Jul 2024 · 31 months · monthly snapshotTerminated~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshotTerminated~Sep 2024 – ~Sep 2025 · 12 months · monthly snapshotTerminated~Sep 2025 – present · 11 months · monthly snapshotTerminated

Change History

10 versions recorded
  1. Sep 2025 — Present [monthly]

    Terminated PHASE3

  2. Sep 2024 — Sep 2025 [monthly]

    Terminated PHASE3

  3. Jul 2024 — Sep 2024 [monthly]

    Terminated PHASE3

  4. Dec 2021 — Jul 2024 [monthly]

    Terminated PHASE3

  5. Jan 2021 — Dec 2021 [monthly]

    Terminated PHASE3

Show 5 earlier versions
  1. Nov 2020 — Jan 2021 [monthly]

    Terminated PHASE3

  2. Jun 2018 — Nov 2020 [monthly]

    Terminated PHASE3

  3. May 2018 — Jun 2018 [monthly]

    Terminated PHASE3

  4. Aug 2017 — May 2018 [monthly]

    Terminated PHASE3

  5. Jan 2017 — Aug 2017 [monthly]

    Terminated PHASE3

    First recorded

Sep 2005

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • AstraZeneca
Data source: AstraZeneca

For direct contact, visit the study record on ClinicalTrials.gov .