Completed PHASE3 INTERVENTIONAL 2-arm NCT00235729

Lofexidine for Inpatient Opiate Detox

CSP #1024 - A Phase III, Randomized, Multi-Center, Double Blind, Placebo-Controlled Study of Safety and Efficacy of Lofexidine for Relief of Symptoms in Subjects Undergoing Inpatient Opiate Detoxification.

Sponsor: National Institute on Drug Abuse (NIDA)

Conditions Opiate Addiction

Interventions Lofexidine Placebo

Updated 9 times since 2017 Last updated: Mar 19, 2009 Started: Jun 30, 2006 Primary completion: Oct 31, 2007 Completion: Oct 31, 2007

This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

A PHASE3 clinical study on Opiate Addiction, this trial is completed. The trial is conducted by National Institute on Drug Abuse (NIDA) and has accumulated 9 data snapshots since 2006. Longitudinal tracking of this trial contributes to a broader understanding of treatment development timelines.

Status Flow

Change History

9 versions recorded

Sep 2025 — Present [monthly]

Completed PHASE3
Sep 2024 — Sep 2025 [monthly]

Completed PHASE3
Jul 2024 — Sep 2024 [monthly]

Completed PHASE3
Mar 2022 — Jul 2024 [monthly]

Completed PHASE3
Jan 2021 — Mar 2022 [monthly]

Completed PHASE3

▶ Show 4 earlier versions

Aug 2018 — Jan 2021 [monthly]

Completed PHASE3
Jun 2018 — Aug 2018 [monthly]

Completed PHASE3
Feb 2017 — Jun 2018 [monthly]

Completed PHASE3
Jan 2017 — Feb 2017 [monthly]

Completed PHASE3

First recorded

Jun 2006

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:

National Institute on Drug Abuse (NIDA)
US Department of Veterans Affairs
USWM, LLC (dba US WorldMeds)

Data source: VA Office of Research and Development

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations

Atlanta, United States , Baltimore, United States , Cerritos, United States , Dallas, United States , Detroit, United States , Hoffman Estates, United States , Lexington, United States , Nashville, United States , Philadelphia, United States , Providence, United States and 6 more locations