Terminated PHASE3 INTERVENTIONAL 2-arm NCT00262821

Cisplatin and Radiation Therapy With or Without Tirapazamine in Treating Patients With Cervical Cancer

A Phase III, Randomized Trial of Weekly Cisplatin and Radiation Versus Cisplatin and Tirapazamine and Radiation in Stage IB2, IIA, IIIB and IVA Cervical Carcinoma Limited to the Pelvis

Sponsor: Gynecologic Oncology Group

Conditions Cervical Adenocarcinoma Cervical Adenosquamous Cell Carcinoma Cervical Squamous Cell Carcinoma Stage IB Cervical Cancer Stage IIA Cervical Cancer Stage IIB Cervical Cancer Stage III Cervical Cancer Stage IVA Cervical Cancer

Interventions cisplatin tirapazamine

Updated 10 times since 2017 Last updated: Jul 19, 2019 Started: Feb 28, 2006 Primary completion: Aug 31, 2010 Completion: Aug 31, 2010

This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Terminated

Study drug no longer available resulting in lack of study drug for participants.

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This PHASE3 trial investigates Cervical Adenocarcinoma and Cervical Adenosquamous Cell Carcinoma and is currently terminated or withdrawn. Gynecologic Oncology Group leads this study, which shows 10 recorded versions since 2006 — indicating substantial longitudinal coverage. As an oncology study, it adds to the longitudinal record of treatment development for this indication.

Status Flow

Change History

10 versions recorded

Sep 2025 — Present [monthly]

Terminated PHASE3
Sep 2024 — Sep 2025 [monthly]

Terminated PHASE3
Jul 2024 — Sep 2024 [monthly]

Terminated PHASE3
Dec 2021 — Jul 2024 [monthly]

Terminated PHASE3
Jan 2021 — Dec 2021 [monthly]

Terminated PHASE3

▶ Show 5 earlier versions

Aug 2019 — Jan 2021 [monthly]

Terminated PHASE3
Jun 2018 — Aug 2019 [monthly]

Terminated PHASE3
Aug 2017 — Jun 2018 [monthly]

Terminated PHASE3

Status: Completed → Terminated
Feb 2017 — Aug 2017 [monthly]

Completed PHASE3
Jan 2017 — Feb 2017 [monthly]

Completed PHASE3

First recorded

Feb 2006

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:

Gynecologic Oncology Group
NCIC Clinical Trials Group
National Cancer Institute (NCI)

Data source: National Cancer Institute (NCI)

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations

Abington, United States , Akron, United States , Albany, United States , Albuquerque, United States , Allentown, United States , Amarillo, United States , American Fork, United States , Ames, United States , Anchorage, United States , Annandale, United States and 190 more locations