Completed PHASE3 INTERVENTIONAL 2-arm NCT00268957

Study to Compare Sevelamer Carbonate Powder to Sevelamer Hydrochloride Tablets in Patients With CKD on Hemodialysis

A Randomized, Parallel, Open-Label Study to Compare Once Per Day Sevelamer Carbonate Powder Dosing With Three Times Per Day Sevelamer Hydrochloride Tablet Dosing in Chronic Kidney Disease Patients on Hemodialysis

Sponsor: Genzyme, a Sanofi Company

Conditions Chronic Renal Insufficiency End-Stage Renal Disease Kidney Diseases

Interventions Sevelamer carbonate (Renvela®) Sevelamer hydrochloride (Renagel®)

Updated 6 times since 2017 Last updated: Mar 17, 2014 Started: Jan 31, 2006 Primary completion: Mar 31, 2007 Completion: May 31, 2007

This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

A PHASE3 clinical study on Chronic Renal Insufficiency and End-Stage Renal Disease, this trial is completed. The trial is conducted by Genzyme, a Sanofi Company and has accumulated 6 data snapshots since 2006. Longitudinal tracking of this trial contributes to a broader understanding of treatment development timelines.

Status Flow

Change History

6 versions recorded

Sep 2025 — Present [monthly]

Completed PHASE3
Sep 2024 — Sep 2025 [monthly]

Completed PHASE3
Jul 2024 — Sep 2024 [monthly]

Completed PHASE3
Jan 2021 — Jul 2024 [monthly]

Completed PHASE3
Jun 2018 — Jan 2021 [monthly]

Completed PHASE3

▶ Show 1 earlier version

Jan 2017 — Jun 2018 [monthly]

Completed PHASE3

First recorded

Jan 2006

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:

Genzyme, a Sanofi Company

Data source: Sanofi

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations

Atlanta, United States , Birmingham, United States , Brookhaven, United States , Charlottesville, United States , Cincinnati, United States , Cleveland, United States , Columbus, United States , Crystal River, United States , Decatur, United States , Detroit, United States and 19 more locations