Completed NA INTERVENTIONAL 4-arm NCT00282672

Ablation of Intestinal Metaplasia Containing Dysplasia

Ablation of Intestinal Metaplasia Containing Dysplasia (AIM Dysplasia Trial) A Multi-center, Randomized, Sham-Controlled Trial: Protocol Amendment to Extend Follow-up to 5 Years

Sponsor: AstraZeneca

Conditions Barrett Esophagus

Interventions Ablation System plus anti-secretory medication Sham procedure plus anti-secretory medication

Updated 10 times since 2017 Last updated: Oct 5, 2017 Started: Feb 28, 2006 Primary completion: Apr 30, 2014 Completion: Aug 31, 2014

This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

This NA trial investigates Barrett Esophagus and is currently completed. AstraZeneca leads this study, which shows 10 recorded versions since 2006 — indicating substantial longitudinal coverage. The change history captured here reflects the iterative nature of clinical trial conduct.

Status Flow

Change History

10 versions recorded

Sep 2025 — Present [monthly]

Completed NA
Sep 2024 — Sep 2025 [monthly]

Completed NA
Jul 2024 — Sep 2024 [monthly]

Completed NA
Jan 2023 — Jul 2024 [monthly]

Completed NA
Dec 2022 — Jan 2023 [monthly]

Completed NA

▶ Show 5 earlier versions

Jan 2021 — Dec 2022 [monthly]

Completed NA
Jun 2018 — Jan 2021 [monthly]

Completed NA
Dec 2017 — Jun 2018 [monthly]

Completed NA
Feb 2017 — Dec 2017 [monthly]

Completed NA
Jan 2017 — Feb 2017 [monthly]

Completed NA

First recorded

Feb 2006

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:

AstraZeneca
Medtronic - MITG

Data source: Medtronic - MITG

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations

Chapel Hill, United States , Charleston, United States , Cleveland, United States , Dallas, United States , Jacksonville, United States , Kansas City, United States , Knoxville, United States , Lebanon, United States , New York, United States , Orange, United States and 8 more locations