Completed PHASE3 INTERVENTIONAL NCT00293358

Combination Chemotherapy and Radiation Therapy in Treating Patients With Germ Cell Tumors in the Brain

SIOP Intracranial Germ Cell Tumours Protocol

Sponsor: Children's Cancer and Leukaemia Group

Conditions Brain and Central Nervous System Tumors

Interventions adjuvant therapy carboplatin cisplatin conventional surgery etoposide phosphate ifosfamide neoadjuvant therapy radiation therapy

Updated 6 times since 2017 Last updated: Sep 16, 2013 Started: Jan 31, 1997 Completion: Dec 31, 2006

This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

This PHASE3 trial investigates Brain and Central Nervous System Tumors and is currently completed. Children's Cancer and Leukaemia Group leads this study, which shows 6 recorded versions since 1997 — indicating limited longitudinal coverage. As an oncology study, it adds to the longitudinal record of treatment development for this indication.

Status Flow

Change History

6 versions recorded

Sep 2025 — Present [monthly]

Completed PHASE3
Sep 2024 — Sep 2025 [monthly]

Completed PHASE3
Jul 2024 — Sep 2024 [monthly]

Completed PHASE3
Jan 2021 — Jul 2024 [monthly]

Completed PHASE3
Jun 2018 — Jan 2021 [monthly]

Completed PHASE3

▶ Show 1 earlier version

Jan 2017 — Jun 2018 [monthly]

Completed PHASE3

First recorded

Jan 1997

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:

Children's Cancer and Leukaemia Group

Data source: National Cancer Institute (NCI)

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations

Aberdeen, United Kingdom , Belfast, United Kingdom , Birmingham, United Kingdom , Bristol, United Kingdom , Cambridge, United Kingdom , Cardiff, United Kingdom , Dublin, Ireland , Edinburgh, United Kingdom , Glasgow, United Kingdom , Leeds, United Kingdom and 10 more locations