deltatrials
Terminated PHASE3 INTERVENTIONAL 2-arm NCT00310830

Efficacy and Safety of Bosentan in Sickle Cell Disease (SCD) Patients With Pulmonary Arterial Hypertension (PAH)

Randomized, Placebo-controlled, Double-blind, Multicenter, Parallel Group Study to Assess the Efficacy, Safety and Tolerability of Bosentan in Patients With Symptomatic Pulmonary Arterial Hypertension Associated With Sickle Cell Disease

Sponsor: Actelion

Interventions Bosentan
Updated 8 times since 2017 Last updated: Jan 31, 2025 Started: Mar 31, 2006 Primary completion: Aug 31, 2007 Completion: Aug 31, 2007
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Terminated

Slow enrollment

This PHASE3 trial investigates Pulmonary Hypertension and is currently terminated or withdrawn. Actelion leads this study, which shows 8 recorded versions since 2006 — indicating limited longitudinal coverage. Heart and vascular conditions benefit from the kind of long-term tracking this trial provides.

Status Flow

~Jan 2017 – ~Feb 2017 · 31 days · monthly snapshotTerminated~Feb 2017 – ~Jun 2018 · 16 months · monthly snapshotTerminated~Jun 2018 – ~Jan 2021 · 31 months · monthly snapshotTerminated~Jan 2021 – ~Apr 2022 · 15 months · monthly snapshotTerminated~Apr 2022 – ~Jul 2024 · 27 months · monthly snapshotTerminated~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshotTerminated~Sep 2024 – ~Mar 2025 · 6 months · monthly snapshotTerminated~Mar 2025 – present · 18 months · monthly snapshotTerminated

Change History

8 versions recorded
  1. Mar 2025 — Present [monthly]

    Terminated PHASE3

  2. Sep 2024 — Mar 2025 [monthly]

    Terminated PHASE3

  3. Jul 2024 — Sep 2024 [monthly]

    Terminated PHASE3

  4. Apr 2022 — Jul 2024 [monthly]

    Terminated PHASE3

  5. Jan 2021 — Apr 2022 [monthly]

    Terminated PHASE3

Show 3 earlier versions
  1. Jun 2018 — Jan 2021 [monthly]

    Terminated PHASE3

  2. Feb 2017 — Jun 2018 [monthly]

    Terminated PHASE3

  3. Jan 2017 — Feb 2017 [monthly]

    Terminated PHASE3

    First recorded

Mar 2006

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Actelion
Data source: Actelion

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations

No location information available.