deltatrials
Terminated PHASE1 INTERVENTIONAL 1-arm NCT00346632

An Ascending Dose Study of KW-2449 in Acute Leukemias, Myelodysplastic Syndromes, and Chronic Myelogenous Leukemia

Phase I Safety, Pharmacokinetic, and Pharmacodynamic Study of KW-2449 in Acute Leukemias (AML), Myelodysplastic Syndromes (MDS), and Chronic Myelogenous Leukemia (CML)

Sponsor: Kyowa Kirin, Inc.

Interventions KW-2449
Updated 8 times since 2017 Last updated: Apr 23, 2024 Started: Jun 30, 2006 Primary completion: Apr 30, 2008 Completion: Apr 30, 2008
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Terminated

Terminated due to suboptimal dosing schedule

This PHASE1 trial investigates Acute Lymphoblastic Leukemia and Acute Myelogenous Leukemia and is currently terminated or withdrawn. Kyowa Kirin, Inc. leads this study, which shows 8 recorded versions since 2006 — indicating limited longitudinal coverage. As an oncology study, it adds to the longitudinal record of treatment development for this indication.

Status Flow

~Jan 2017 – ~Feb 2017 · 31 days · monthly snapshotTerminated~Feb 2017 – ~Jun 2018 · 16 months · monthly snapshotTerminated~Jun 2018 – ~Jan 2021 · 31 months · monthly snapshotTerminated~Jan 2021 – ~Oct 2021 · 9 months · monthly snapshotTerminated~Oct 2021 – ~Jun 2024 · 32 months · monthly snapshotTerminated~Jun 2024 – ~Jul 2024 · 30 days · monthly snapshotTerminated~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshotTerminated~Sep 2024 – present · 22 months · monthly snapshotTerminated

Change History

8 versions recorded
  1. Sep 2024 — Present [monthly]

    Terminated PHASE1

  2. Jul 2024 — Sep 2024 [monthly]

    Terminated PHASE1

  3. Jun 2024 — Jul 2024 [monthly]

    Terminated PHASE1

  4. Oct 2021 — Jun 2024 [monthly]

    Terminated PHASE1

  5. Jan 2021 — Oct 2021 [monthly]

    Terminated PHASE1

Show 3 earlier versions
  1. Jun 2018 — Jan 2021 [monthly]

    Terminated PHASE1

  2. Feb 2017 — Jun 2018 [monthly]

    Terminated PHASE1

  3. Jan 2017 — Feb 2017 [monthly]

    Terminated PHASE1

    First recorded

Jun 2006

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Kyowa Kirin, Inc.
Data source: Kyowa Kirin Co., Ltd.

For direct contact, visit the study record on ClinicalTrials.gov .