Radial Optic Neurotomy in Central Retinal Vein Occlusion : a Randomized Trial (OVCR)
Multicenter Trial to Investigate the Safety and Efficacy of Vitrectomy With Radial Optic Neurotomy for the Preservation of Visual Function in Subjects With Central Retinal Vein Occlusion (CRVO)
Sponsor: University Hospital, Bordeaux
Terminated
lack of recruting
Listed as NCT00379223, this NA trial focuses on Retinal Vein Occlusion and remains terminated or withdrawn. Sponsored by University Hospital, Bordeaux, it has been updated 6 times since 2006, reflecting limited change activity. This study adds to the evidence base for this therapeutic area through structured, versioned documentation.
Study Description(click to expand)Central Retinal Vein Occlusion (CRVO) is the second most frequently retinal vascular disease causing loss of vision, after diabetic retinopathy. No treatment of CRVO has clearly demonstrated beneficial and long lasting visual results. Commonly used treatment options are platelet anti-aggregating agents, correcting rheologic factors with troxerutin and isovolumic hemodilution. Surgical treatment of CRVO has recently been proposed (2001) and has been studied in numerous non comparative pilot studies. Limited but encouraging results motivate our randomised controlled trial. We will evaluate at 6 months visual acuity after surgery associating pars plana vitrectomy and radial optic neurotomy, in patients with central vein occlusion and bad vision, associated with the correction of rheologic factors.
Central Retinal Vein Occlusion (CRVO) is the second most frequently retinal vascular disease causing loss of vision, after diabetic retinopathy. No treatment of CRVO has clearly demonstrated beneficial and long lasting visual results. Commonly used treatment options are platelet anti-aggregating agents, correcting rheologic factors with troxerutin and isovolumic hemodilution. Surgical treatment of CRVO has recently been proposed (2001) and has been studied in numerous non comparative pilot studies. Limited but encouraging results motivate our randomised controlled trial. We will evaluate at 6 months visual acuity after surgery associating pars plana vitrectomy and radial optic neurotomy, in patients with central vein occlusion and bad vision, associated with the correction of rheologic factors.
Status Flow
Change History
6 versions recorded-
Jan 2026 — Present [monthly]
Terminated NA
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Sep 2024 — Present [monthly]
Terminated NA
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Jul 2024 — Sep 2024 [monthly]
Terminated NA
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Jan 2021 — Jul 2024 [monthly]
Terminated NA
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Jun 2018 — Jan 2021 [monthly]
Terminated NA
▶ Show 1 earlier version
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Jan 2017 — Jun 2018 [monthly]
Terminated NA
First recorded
Oct 2006
Trial started
Per CT.gov start date — pre-dates our first snapshot
Eligibility Summary
No eligibility information available.
Contact Information
- University Hospital, Bordeaux
For direct contact, visit the study record on ClinicalTrials.gov .