Terminated PHASE2 INTERVENTIONAL 1-arm NCT00389090

A Phase II Study of Temozolomide and O6-Benzylguanine (O6-BG) in Patients With Temozolomide-Resistant Anaplastic Glioma

Sponsor: Keryx / AOI Pharmaceuticals, Inc.

Conditions Astrocytoma Glioma Oligoastrocytoma Oligodendroglioma

Interventions Temozolomide and O6-Benzylguanine

Updated 6 times since 2017 Last updated: Feb 7, 2012 Started: Oct 31, 2006 Primary completion: Jun 30, 2008 Completion: Feb 28, 2009

This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Terminated

AOI Pharma terminated the license agreement. IND Transferred to NCI

Listed as NCT00389090, this PHASE2 trial focuses on Astrocytoma and Glioma and remains terminated or withdrawn. Sponsored by Keryx / AOI Pharmaceuticals, Inc., it has been updated 6 times since 2006, reflecting limited change activity. This study adds to the evidence base for this therapeutic area through structured, versioned documentation.

Status Flow

Change History

6 versions recorded

Sep 2024 — Present [monthly]

Terminated PHASE2
Jul 2024 — Sep 2024 [monthly]

Terminated PHASE2
Jan 2021 — Jul 2024 [monthly]

Terminated PHASE2
Jun 2018 — Jan 2021 [monthly]

Terminated PHASE2
Feb 2017 — Jun 2018 [monthly]

Terminated PHASE2

▶ Show 1 earlier version

Jan 2017 — Feb 2017 [monthly]

Terminated PHASE2

First recorded

Oct 2006

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:

Keryx / AOI Pharmaceuticals, Inc.

Data source: Keryx / AOI Pharmaceuticals, Inc.

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations

Chicago, United States , Dallas, United States , Durham, United States , Evanston, United States , Greenville, United States , Houston, United States , Lexington, United States , Los Angeles, United States , Louisville, United States , Minneapolis, United States and 2 more locations