deltatrials
Terminated PHASE3 INTERVENTIONAL 2-arm NCT00395161

The CRISIS Prevention Study (CRISIS)

The Critical Illness Stress-induced Immune Suppression Prevention Trial

Sponsor: Arkansas Children's Hospital Research Institute

Conditions Sepsis
Interventions Glutamine Metoclopramide Selenium Zinc saline selenium sterile water whey-protein
Updated 11 times since 2017 Last updated: Apr 16, 2013 Started: Apr 30, 2007 Primary completion: Nov 30, 2009 Completion: Nov 30, 2009
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Terminated

Terminated for futility on 11/30/09 based on the recommendation of the DSMB

Other terminated trials from Arkansas Children's Hospital Research Institute

See all terminations from Arkansas Children's Hospital Research Institute

A PHASE3 clinical study on Sepsis, this trial is terminated or withdrawn. The trial is conducted by Arkansas Children's Hospital Research Institute and has accumulated 11 data snapshots since 2007. Longitudinal tracking of this trial contributes to a broader understanding of treatment development timelines.

Status Flow

~Jan 2017 – ~Feb 2017 · 31 days · monthly snapshotTerminated~Feb 2017 – ~Jun 2018 · 16 months · monthly snapshotTerminated~Jun 2018 – ~Mar 2020 · 21 months · monthly snapshotTerminated~Mar 2020 – ~Jan 2021 · 10 months · monthly snapshotTerminated~Jan 2021 – ~Dec 2021 · 11 months · monthly snapshotTerminated~Dec 2021 – ~Dec 2022 · 12 months · monthly snapshotTerminated~Dec 2022 – ~Jan 2023 · 31 days · monthly snapshotTerminated~Jan 2023 – ~Jul 2024 · 18 months · monthly snapshotTerminated~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshotTerminated~Sep 2024 – ~Sep 2025 · 12 months · monthly snapshotTerminated~Sep 2025 – present · 12 months · monthly snapshotTerminated

Change History

11 versions recorded

  1. Sep 2025 — Present [monthly]

    Terminated PHASE3

  2. Sep 2024 — Sep 2025 [monthly]

    Terminated PHASE3

  3. Jul 2024 — Sep 2024 [monthly]

    Terminated PHASE3

  4. Jan 2023 — Jul 2024 [monthly]

    Terminated PHASE3

  5. Dec 2022 — Jan 2023 [monthly]

    Terminated PHASE3

▶ Show 6 earlier versions

  1. Dec 2021 — Dec 2022 [monthly]

    Terminated PHASE3

  2. Jan 2021 — Dec 2021 [monthly]

    Terminated PHASE3

  3. Mar 2020 — Jan 2021 [monthly]

    Terminated PHASE3

  4. Jun 2018 — Mar 2020 [monthly]

    Terminated PHASE3

  5. Feb 2017 — Jun 2018 [monthly]

    Terminated PHASE3

  6. Jan 2017 — Feb 2017 [monthly]

    Terminated PHASE3

    First recorded

Apr 2007

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Arkansas Children's Hospital Research Institute
  • Children's Hospital Los Angeles
  • Children's Hospital of Michigan
  • Children's National Research Institute
  • Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
  • Harborview Injury Prevention and Research Center
  • Michael Dean
  • Seattle Children's Hospital
  • University of California, Los Angeles
  • University of Pittsburgh
Data source: University of Utah

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations