deltatrials
Completed PHASE4 INTERVENTIONAL 2-arm NCT00414635

FOTO: Five Consecutive Days on Treatment With Efavirenz, Tenofovir, and Emtricitabine Followed by Two Days Off Treatment Versus Continuous Treatment

A Randomized Controlled Trial of a Weekly Schedule of Five Consecutive Days on Treatment With Efavirenz, Tenofovir, and Emtricitabine Followed by Two Days Off Treatment (5/2 Intermittent Treatment Schedule) Versus Continuous Treatment in Individuals With Virologic Suppression on This Combination

Sponsor: Community Research Initiative of New England

Conditions HIV Infections
Interventions Intermitent Dosing
Updated 10 times since 2017 Last updated: Aug 24, 2017 Started: Aug 31, 2006 Primary completion: Dec 31, 2009 Completion: Dec 31, 2009
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Listed as NCT00414635, this PHASE4 trial focuses on HIV Infections and remains completed. Sponsored by Community Research Initiative of New England, it has been updated 10 times since 2006, reflecting substantial change activity. This study is part of the global effort to build evidence for infectious disease interventions.

Status Flow

~Jan 2017 – ~Sep 2017 · 8 months · monthly snapshotCompleted~Sep 2017 – ~Jun 2018 · 9 months · monthly snapshotCompleted~Jun 2018 – ~Jan 2021 · 31 months · monthly snapshotCompleted~Jan 2021 – ~Dec 2021 · 11 months · monthly snapshotCompleted~Dec 2021 – ~Dec 2022 · 12 months · monthly snapshotCompleted~Dec 2022 – ~Jan 2023 · 31 days · monthly snapshotCompleted~Jan 2023 – ~Jul 2024 · 18 months · monthly snapshotCompleted~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshotCompleted~Sep 2024 – ~Sep 2025 · 12 months · monthly snapshotCompleted~Sep 2025 – present · 12 months · monthly snapshotCompleted

Change History

10 versions recorded
  1. Sep 2025 — Present [monthly]

    Completed PHASE4

  2. Sep 2024 — Sep 2025 [monthly]

    Completed PHASE4

  3. Jul 2024 — Sep 2024 [monthly]

    Completed PHASE4

  4. Jan 2023 — Jul 2024 [monthly]

    Completed PHASE4

  5. Dec 2022 — Jan 2023 [monthly]

    Completed PHASE4

Show 5 earlier versions
  1. Dec 2021 — Dec 2022 [monthly]

    Completed PHASE4

  2. Jan 2021 — Dec 2021 [monthly]

    Completed PHASE4

  3. Jun 2018 — Jan 2021 [monthly]

    Completed PHASE4

  4. Sep 2017 — Jun 2018 [monthly]

    Completed PHASE4

  5. Jan 2017 — Sep 2017 [monthly]

    Completed PHASE4

    First recorded

Aug 2006

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Community Research Initiative of New England
  • The Campbell Foundation
Data source: Community Research Initiative of New England

For direct contact, visit the study record on ClinicalTrials.gov .