deltatrials
Terminated PHASE4 INTERVENTIONAL 4-arm NCT00430716

To Assess The Efficacy and Safety Of Oral Sildenafil in the Treatment of Pulmonary Arterial Hypertension.

A MULTINATIONAL, MULTICENTRE, RANDOMIZED, PARALLEL GROUP, DOUBLE-BLIND STUDY TO ASSESS THE EFFICACY AND SAFETY OF 1MG, 5MG AND 20 MG TID OF ORAL SILDENAFIL IN THE TREATMENT OF SUBJECTS AGED 18 YEARS AND OVER WITH PULMONARY ARTERIAL HYPERTENSION (PAH)

Sponsor: Pfizer's Upjohn has merged with Mylan to form Viatris Inc.

Interventions Sildenafil citrate
Updated 11 times since 2017 Last updated: Dec 18, 2020 Started: Apr 8, 2008 Primary completion: May 25, 2010 Completion: May 25, 2010
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Terminated

This study was terminated at the recommendation of an independent Data Monitoring Committee. The decision was not based on any safety concerns.

This PHASE4 trial investigates Pulmonary Arterial Hypertension and is currently terminated or withdrawn. Pfizer's Upjohn has merged with Mylan to form Viatris Inc. leads this study, which shows 11 recorded versions since 2008 — indicating substantial longitudinal coverage. Heart and vascular conditions benefit from the kind of long-term tracking this trial provides.

Status Flow

~Jan 2017 – ~Feb 2017 · 31 days · monthly snapshotTerminated~Feb 2017 – ~Aug 2017 · 6 months · monthly snapshotTerminated~Aug 2017 – ~May 2018 · 9 months · monthly snapshotTerminated~May 2018 – ~Jun 2018 · 31 days · monthly snapshotTerminated~Jun 2018 – ~Nov 2020 · 29 months · monthly snapshotTerminated~Nov 2020 – ~Jan 2021 · 2 months · monthly snapshotTerminated~Jan 2021 – ~Dec 2021 · 11 months · monthly snapshotTerminated~Dec 2021 – ~Jul 2024 · 31 months · monthly snapshotTerminated~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshotTerminated~Sep 2024 – ~Sep 2025 · 12 months · monthly snapshotTerminated~Sep 2025 – present · 7 months · monthly snapshotTerminated

Change History

11 versions recorded
  1. Sep 2025 — Present [monthly]

    Terminated PHASE4

  2. Sep 2024 — Sep 2025 [monthly]

    Terminated PHASE4

  3. Jul 2024 — Sep 2024 [monthly]

    Terminated PHASE4

  4. Dec 2021 — Jul 2024 [monthly]

    Terminated PHASE4

  5. Jan 2021 — Dec 2021 [monthly]

    Terminated PHASE4

Show 6 earlier versions
  1. Nov 2020 — Jan 2021 [monthly]

    Terminated PHASE4

  2. Jun 2018 — Nov 2020 [monthly]

    Terminated PHASE4

  3. May 2018 — Jun 2018 [monthly]

    Terminated PHASE4

  4. Aug 2017 — May 2018 [monthly]

    Terminated PHASE4

  5. Feb 2017 — Aug 2017 [monthly]

    Terminated PHASE4

  6. Jan 2017 — Feb 2017 [monthly]

    Terminated PHASE4

    First recorded

Apr 2008

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Data source: Pfizer

For direct contact, visit the study record on ClinicalTrials.gov .