deltatrials
Unknown PHASE2 INTERVENTIONAL NCT00434369

5-Fluorouracil Combined With CoFactor (5-10 Methylenetetrahydrofolate) in Treating Advanced Breast Cancer Patients

A Multi-Center, Open-Label, Single-Arm Phase II Trial Assessing the Efficacy and Safety of Weekly Bolus Infusions of 5-Fluorouracil Combined With CoFactor (5-10 Methylenetetrahydrofolate) in Advanced Breast Cancer Patients Who Failed Anthracycline and Taxane Chemotherapy Regimens

Sponsor: Mast Therapeutics, Inc.

Conditions Breast Cancer
Interventions CoFactor (ANX-510)
Updated 8 times since 2017 Last updated: Apr 18, 2008 Started: Feb 28, 2006
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Listed as NCT00434369, this PHASE2 trial focuses on Breast Cancer and remains ongoing. Sponsored by Mast Therapeutics, Inc., it has been updated 8 times since 2006, reflecting limited change activity. This study contributes to the evolving evidence base for cancer treatment protocols.

Status Flow

~Jan 2017 – ~Feb 2017 · 31 days · monthly snapshotUnknown Status~Feb 2017 – ~Jun 2018 · 16 months · monthly snapshotUnknown Status~Jun 2018 – ~Jan 2021 · 31 months · monthly snapshotUnknown Status~Jan 2021 – ~Jul 2024 · 42 months · monthly snapshotUnknown Status~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshotUnknown~Sep 2024 – ~Sep 2025 · 12 months · monthly snapshotUnknown~Sep 2025 – present · 7 months · monthly snapshotUnknown~Jan 2026 – present · 3 months · monthly snapshotUnknown

Change History

8 versions recorded
  1. Jan 2026 — Present [monthly]

    Unknown PHASE2

  2. Sep 2025 — Present [monthly]

    Unknown PHASE2

  3. Sep 2024 — Sep 2025 [monthly]

    Unknown PHASE2

  4. Jul 2024 — Sep 2024 [monthly]

    Unknown PHASE2

    Status: Unknown StatusUnknown

  5. Jan 2021 — Jul 2024 [monthly]

    Unknown Status PHASE2

Show 3 earlier versions
  1. Jun 2018 — Jan 2021 [monthly]

    Unknown Status PHASE2

  2. Feb 2017 — Jun 2018 [monthly]

    Unknown Status PHASE2

  3. Jan 2017 — Feb 2017 [monthly]

    Unknown Status PHASE2

    First recorded

Feb 2006

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Mast Therapeutics, Inc.
Data source: Mast Therapeutics, Inc.

For direct contact, visit the study record on ClinicalTrials.gov .