Completed PHASE2 INTERVENTIONAL 1-arm NCT00458601

Phase II Study of Rindopepimut (CDX-110) in Patients With Glioblastoma Multiforme (ACT III)

A Phase II Study of CDX-110 With Radiation and Temozolomide in Patients With Newly Diagnosed Glioblastoma Multiforme

Sponsor: Celldex Therapeutics

Interventions CDX-110 with GM-CSF Temozolomide

Updated 10 times since 2017 Last updated: Jan 11, 2018 Started: Aug 31, 2007 Primary completion: Nov 30, 2010 Completion: May 31, 2016

This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

This PHASE2 trial investigates Malignant Glioma and is currently completed. Celldex Therapeutics leads this study, which shows 10 recorded versions since 2007 — indicating substantial longitudinal coverage. As an oncology study, it adds to the longitudinal record of treatment development for this indication.

Status Flow

Change History

10 versions recorded

Sep 2025 — Present [monthly]

Completed PHASE2
Sep 2024 — Sep 2025 [monthly]

Completed PHASE2
Jul 2024 — Sep 2024 [monthly]

Completed PHASE2
Apr 2022 — Jul 2024 [monthly]

Completed PHASE2
Jan 2021 — Apr 2022 [monthly]

Completed PHASE2

▶ Show 5 earlier versions

Jun 2018 — Jan 2021 [monthly]

Completed PHASE2
Feb 2018 — Jun 2018 [monthly]

Completed PHASE2
Oct 2017 — Feb 2018 [monthly]

Completed PHASE2
Feb 2017 — Oct 2017 [monthly]

Completed PHASE2
Jan 2017 — Feb 2017 [monthly]

Completed PHASE2

First recorded

Aug 2007

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:

Celldex Therapeutics

Data source: Celldex Therapeutics

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations

Amherst, United States , Boston, United States , Charlottesville, United States , Chicago, United States , Cincinnati, United States , Cleveland, United States , Durham, United States , Evanston, United States , Gainesville, United States , Hackensack, United States and 14 more locations