deltatrials
Terminated PHASE3 INTERVENTIONAL 2-arm NCT00460317

MONET1-MOtesanib NSCLC Efficacy and Tolerability Study

A Phase 3, Multicenter, Randomized, Placebo-Controlled, Double-Blind Trial of AMG 706 in Combination With Paclitaxel and Carboplatin for Advanced Non-small Cell Lung Cancer.

Sponsor: Amgen

Updated 11 times since 2017 Last updated: Aug 24, 2015 Started: Jul 31, 2007 Primary completion: Mar 31, 2011 Completion: Aug 31, 2013
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Terminated

Amgen discontinued the development of AMG706 because 20050201 did not meet its primary objective.

This PHASE3 trial investigates Non-Small Cell Lung Cancer and is currently terminated or withdrawn. Amgen leads this study, which shows 11 recorded versions since 2007 — indicating substantial longitudinal coverage. As an oncology study, it adds to the longitudinal record of treatment development for this indication.

Status Flow

~Jan 2017 – ~Feb 2017 · 31 days · monthly snapshotTerminated~Feb 2017 – ~Aug 2017 · 6 months · monthly snapshotTerminated~Aug 2017 – ~May 2018 · 9 months · monthly snapshotTerminated~May 2018 – ~Jun 2018 · 31 days · monthly snapshotTerminated~Jun 2018 – ~Nov 2020 · 29 months · monthly snapshotTerminated~Nov 2020 – ~Jan 2021 · 2 months · monthly snapshotTerminated~Jan 2021 – ~Dec 2021 · 11 months · monthly snapshotTerminated~Dec 2021 – ~Apr 2022 · 4 months · monthly snapshotTerminated~Apr 2022 – ~Jul 2024 · 27 months · monthly snapshotTerminated~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshotTerminated~Sep 2024 – present · 24 months · monthly snapshotTerminated

Change History

11 versions recorded
  1. Sep 2024 — Present [monthly]

    Terminated PHASE3

  2. Jul 2024 — Sep 2024 [monthly]

    Terminated PHASE3

  3. Apr 2022 — Jul 2024 [monthly]

    Terminated PHASE3

  4. Dec 2021 — Apr 2022 [monthly]

    Terminated PHASE3

  5. Jan 2021 — Dec 2021 [monthly]

    Terminated PHASE3

Show 6 earlier versions
  1. Nov 2020 — Jan 2021 [monthly]

    Terminated PHASE3

  2. Jun 2018 — Nov 2020 [monthly]

    Terminated PHASE3

  3. May 2018 — Jun 2018 [monthly]

    Terminated PHASE3

  4. Aug 2017 — May 2018 [monthly]

    Terminated PHASE3

  5. Feb 2017 — Aug 2017 [monthly]

    Terminated PHASE3

  6. Jan 2017 — Feb 2017 [monthly]

    Terminated PHASE3

    First recorded

Jul 2007

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Amgen
  • Takeda
Data source: Amgen

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations

No location information available.