deltatrials
Terminated PHASE3 INTERVENTIONAL 2-arm NCT00460473

A Research Study to Evaluate the Effectiveness of Dexmedetomidine in Preventing Delirium After Hip Fracture Repair Surgery

A Phase III,Randomized, Double-Blind, Placebo-Controlled, Two-Arm Parallel, Multicenter Study Evaluating the Efficacy and Safety of Dexmedetomidine in the Prevention of Postoperative Delirium in Subjects Undergoing Surgery for Fractured Hip With General Anesthesia

Sponsor: Hospira, now a wholly owned subsidiary of Pfizer

Conditions Delirium
Updated 12 times since 2017 Last updated: Jul 23, 2015 Started: Apr 30, 2007 Primary completion: Nov 30, 2007 Completion: Nov 30, 2007
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Terminated

The incidence of post-operative delirium observed from interim blinded data was significantly lower than the current literature in this population.

This PHASE3 trial investigates Delirium and is currently terminated or withdrawn. Hospira, now a wholly owned subsidiary of Pfizer leads this study, which shows 12 recorded versions since 2007 — indicating substantial longitudinal coverage. The change history captured here reflects the iterative nature of clinical trial conduct.

Status Flow

~Jan 2017 – ~Feb 2017 · 31 days · monthly snapshotTerminated~Feb 2017 – ~May 2017 · 3 months · monthly snapshotTerminated~May 2017 – ~Aug 2017 · 3 months · monthly snapshotTerminated~Aug 2017 – ~May 2018 · 9 months · monthly snapshotTerminated~May 2018 – ~Jun 2018 · 31 days · monthly snapshotTerminated~Jun 2018 – ~Nov 2020 · 29 months · monthly snapshotTerminated~Nov 2020 – ~Jan 2021 · 2 months · monthly snapshotTerminated~Jan 2021 – ~Dec 2021 · 11 months · monthly snapshotTerminated~Dec 2021 – ~Jul 2024 · 31 months · monthly snapshotTerminated~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshotTerminated~Sep 2024 – present · 19 months · monthly snapshotTerminated~Jan 2026 – present · 3 months · monthly snapshotTerminated

Change History

12 versions recorded
  1. Jan 2026 — Present [monthly]

    Terminated PHASE3

  2. Sep 2024 — Present [monthly]

    Terminated PHASE3

  3. Jul 2024 — Sep 2024 [monthly]

    Terminated PHASE3

  4. Dec 2021 — Jul 2024 [monthly]

    Terminated PHASE3

  5. Jan 2021 — Dec 2021 [monthly]

    Terminated PHASE3

Show 7 earlier versions
  1. Nov 2020 — Jan 2021 [monthly]

    Terminated PHASE3

  2. Jun 2018 — Nov 2020 [monthly]

    Terminated PHASE3

  3. May 2018 — Jun 2018 [monthly]

    Terminated PHASE3

  4. Aug 2017 — May 2018 [monthly]

    Terminated PHASE3

  5. May 2017 — Aug 2017 [monthly]

    Terminated PHASE3

  6. Feb 2017 — May 2017 [monthly]

    Terminated PHASE3

  7. Jan 2017 — Feb 2017 [monthly]

    Terminated PHASE3

    First recorded

Apr 2007

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Hospira, now a wholly owned subsidiary of Pfizer
Data source: Hospira, now a wholly owned subsidiary of Pfizer

For direct contact, visit the study record on ClinicalTrials.gov .