Completed PHASE3 INTERVENTIONAL 2-arm NCT00465738

IncobotulinumtoxinA (Xeomin) for Upper Limb Spasticity (NT-Spin)

Prospective, Randomized, Observer-blind, Parallel-group, Multi-center Trial to Assess Efficacy and Safety of Two Different Dilutions of incobotulinumtoxinA (Xeomin) in Patients With Upper Limb Spasticity

Sponsor: Merz Pharmaceuticals GmbH

Conditions Upper Limb Spasticity

Interventions incobotulinumtoxinA (Xeomin, also known as NT 201 or Botulinum toxin type A (150 kD), free from complexing proteins)

Updated 7 times since 2017 Last updated: Dec 21, 2010 Started: Feb 28, 2007 Primary completion: Jan 31, 2008 Completion: May 31, 2008

This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

This PHASE3 trial investigates Upper Limb Spasticity and is currently completed. Merz Pharmaceuticals GmbH leads this study, which shows 7 recorded versions since 2007 — indicating limited longitudinal coverage. The change history captured here reflects the iterative nature of clinical trial conduct.

Status Flow

Change History

7 versions recorded

Sep 2025 — Present [monthly]

Completed PHASE3
Sep 2024 — Sep 2025 [monthly]

Completed PHASE3
Jul 2024 — Sep 2024 [monthly]

Completed PHASE3
Jan 2021 — Jul 2024 [monthly]

Completed PHASE3
Jun 2018 — Jan 2021 [monthly]

Completed PHASE3

▶ Show 2 earlier versions

Feb 2017 — Jun 2018 [monthly]

Completed PHASE3
Jan 2017 — Feb 2017 [monthly]

Completed PHASE3

First recorded

Feb 2007

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:

Merz Pharmaceuticals GmbH

Data source: Merz Pharmaceuticals GmbH

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations

Barcelona, Spain , Bari, Italy , Beelitz-Heilstätten, Germany , Bern, Switzerland , Besançon, France , Costa Masnaga, Italy , Düsseldorf, Germany , Garches, France , Gladbeck, Germany , Hermagor, Austria and 17 more locations