Completed PHASE3 INTERVENTIONAL 2-arm NCT00466947

COMPAS (Clinical Otitis Media & Pneumonia Study): Pneumonia & Acute Otitis Media (AOM ) Efficacy Study of the Pneumococcal Conjugate Vaccine

COMPAS: A Phase III Study to Demonstrate Efficacy of GSK Biologicals' 10-valent Pneumococcal Vaccine (GSK1024850A) Against Community Acquired Pneumonia and Acute Otitis Media

Sponsor: GlaxoSmithKline

Conditions Infections, Streptococcal

Interventions Engerix-B GSK Biologicals' DTPa-IPV/Hib vaccine Havrix Infanrix hexa Pneumococcal conjugate vaccine GSK1024850A

Updated 10 times since 2017 Last updated: Jul 2, 2019 Started: Jun 28, 2007 Primary completion: Aug 31, 2010 Completion: Jul 28, 2011

This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

This PHASE3 trial investigates Infections, Streptococcal and is currently completed. GlaxoSmithKline leads this study, which shows 10 recorded versions since 2007 — indicating substantial longitudinal coverage. Longitudinal tracking of infectious disease trials helps identify durability of treatment effects.

Status Flow

Change History

10 versions recorded

Nov 2025 — Present [monthly]

Completed PHASE3
Sep 2025 — Nov 2025 [monthly]

Completed PHASE3
Sep 2024 — Sep 2025 [monthly]

Completed PHASE3
Jul 2024 — Sep 2024 [monthly]

Completed PHASE3
Jan 2021 — Jul 2024 [monthly]

Completed PHASE3

▶ Show 5 earlier versions

Aug 2019 — Jan 2021 [monthly]

Completed PHASE3
Jun 2019 — Aug 2019 [monthly]

Completed PHASE3
Jun 2018 — Jun 2019 [monthly]

Completed PHASE3
Feb 2017 — Jun 2018 [monthly]

Completed PHASE3
Jan 2017 — Feb 2017 [monthly]

Completed PHASE3

First recorded

Jun 2007

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:

GlaxoSmithKline

Data source: GlaxoSmithKline

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations

Albardón, Argentina , Cali, Colombia , Caucete, Argentina , Córdoba, Argentina , Fernández, Argentina , Godoy Cruz, Argentina , La Banda, Argentina , Las Heras, Argentina , Luján de Cuyo, Argentina , Maipú, Argentina and 7 more locations