Completed PHASE3 INTERVENTIONAL NCT00499707

Efficacy and Safety Study of Rosiglitazone/Metformin Therapy vs Rosiglitazone and Metformin in Type 2 Diabetes Subjects

A Randomized, Double-blind Trial to Evaluate the Efficacy and Safety of Fixed Dose Rosiglitazone/Metformin Combination Therapy Compared to Both Rosiglitazone and Metformin Monotherapies in Drug Naive Type 2 Diabetes Mellitus Subjects

Sponsor: GlaxoSmithKline

Conditions Diabetes Mellitus, Type 2

Interventions rosiglitazone maleate/metformin hydrochloride

Updated 8 times since 2017 Last updated: Mar 19, 2018 Started: Oct 8, 2003 Primary completion: Dec 1, 2004 Completion: Dec 16, 2004

This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

This PHASE3 trial investigates Diabetes Mellitus, Type 2 and is currently completed. GlaxoSmithKline leads this study, which shows 8 recorded versions since 2003 — indicating limited longitudinal coverage. The change history captured here reflects the iterative nature of clinical trial conduct.

Status Flow

Change History

8 versions recorded

Sep 2025 — Present [monthly]

Completed PHASE3
Sep 2024 — Sep 2025 [monthly]

Completed PHASE3
Jul 2024 — Sep 2024 [monthly]

Completed PHASE3
Jan 2021 — Jul 2024 [monthly]

Completed PHASE3
Jun 2018 — Jan 2021 [monthly]

Completed PHASE3

▶ Show 3 earlier versions

Apr 2018 — Jun 2018 [monthly]

Completed PHASE3
Feb 2017 — Apr 2018 [monthly]

Completed PHASE3
Jan 2017 — Feb 2017 [monthly]

Completed PHASE3

First recorded

Oct 2003

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:

GlaxoSmithKline

Data source: GlaxoSmithKline

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations

Anniston, United States , Arlington, United States , Atlanta, United States , Auckland, New Zealand , Beaumont, United States , Brampton, Canada , Bristol, United States , Bryan, United States , Burlington, Canada , Calgary, Canada and 82 more locations