deltatrials
Terminated PHASE2/PHASE3 INTERVENTIONAL 1-arm NCT00524134

P-glycoprotein Inhibition as Adjunct Treatment for Medically Refractory Epilepsy.

An Open-label Pilot Study Using Carvedilol-CR as a P-glycoprotein Inhibitor as Adjunct Therapy in the Treatment of Medically-refractory Epilepsy

Sponsor: American Epilepsy Society

Conditions Epilepsy
Interventions Carvedilol-CR
Updated 6 times since 2017 Last updated: Apr 21, 2016 Started: Dec 31, 2008 Primary completion: Oct 31, 2010 Completion: Oct 31, 2010
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Terminated

PI left the institution.

A PHASE2/PHASE3 clinical study on Epilepsy, this trial is terminated or withdrawn. The trial is conducted by American Epilepsy Society and has accumulated 6 data snapshots since 2008. Longitudinal tracking of this trial contributes to a broader understanding of treatment development timelines.

Status Flow

~Jan 2017 – ~Jun 2018 · 17 months · monthly snapshotTerminated~Jun 2018 – ~Jan 2021 · 31 months · monthly snapshotTerminated~Jan 2021 – ~Oct 2022 · 21 months · monthly snapshotTerminated~Oct 2022 – ~Jul 2024 · 21 months · monthly snapshotTerminated~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshotTerminated~Sep 2024 – present · 22 months · monthly snapshotTerminated

Change History

6 versions recorded
  1. Sep 2024 — Present [monthly]

    Terminated PHASE2/PHASE3

  2. Jul 2024 — Sep 2024 [monthly]

    Terminated PHASE2/PHASE3

    Phase: PHASE2_PHASE3PHASE2/PHASE3

  3. Oct 2022 — Jul 2024 [monthly]

    Terminated PHASE2_PHASE3

  4. Jan 2021 — Oct 2022 [monthly]

    Terminated PHASE2_PHASE3

  5. Jun 2018 — Jan 2021 [monthly]

    Terminated PHASE2_PHASE3

Show 1 earlier version
  1. Jan 2017 — Jun 2018 [monthly]

    Terminated PHASE2_PHASE3

    First recorded

Dec 2008

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • American Epilepsy Society
  • Columbia University
  • GlaxoSmithKline
  • Milken Institute
Data source: Columbia University

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations