deltatrials
Terminated NA INTERVENTIONAL 2-arm NCT00524862

Standard Drug Therapy vs. Implanted Defibrillator for Primary Prevention of Sudden Cardiac Death (SMART-ICD)

Selective Strategy to Manage Arrhythmia Risk and Therapy With ICD

Sponsor: Institute for Clinical Evaluative Sciences

Conditions Congestive Heart Failure Coronary Heart Disease Low Cardiac Output Sudden Cardiac Death Ventricular Dysfunction
Interventions Implantable Cardioverter Defibrillator Optimized medical therapy
Updated 7 times since 2017 Last updated: Jul 30, 2015 Started: Oct 31, 2007 Primary completion: Apr 30, 2011 Completion: Apr 30, 2011
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Terminated

Poor recruitment

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This NA trial investigates Congestive Heart Failure and Coronary Heart Disease and is currently terminated or withdrawn. Institute for Clinical Evaluative Sciences leads this study, which shows 7 recorded versions since 2007 — indicating limited longitudinal coverage. Heart and vascular conditions benefit from the kind of long-term tracking this trial provides.

Status Flow

~Jan 2017 – ~Jun 2018 · 17 months · monthly snapshotTerminated~Jun 2018 – ~Jan 2021 · 31 months · monthly snapshotTerminated~Jan 2021 – ~Oct 2021 · 9 months · monthly snapshotTerminated~Oct 2021 – ~Jul 2024 · 33 months · monthly snapshotTerminated~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshotTerminated~Sep 2024 – ~Sep 2025 · 12 months · monthly snapshotTerminated~Sep 2025 – present · 10 months · monthly snapshotTerminated

Change History

7 versions recorded

  1. Sep 2025 — Present [monthly]

    Terminated NA

  2. Sep 2024 — Sep 2025 [monthly]

    Terminated NA

  3. Jul 2024 — Sep 2024 [monthly]

    Terminated NA

  4. Oct 2021 — Jul 2024 [monthly]

    Terminated NA

  5. Jan 2021 — Oct 2021 [monthly]

    Terminated NA

▶ Show 2 earlier versions

  1. Jun 2018 — Jan 2021 [monthly]

    Terminated NA

  2. Jan 2017 — Jun 2018 [monthly]

    Terminated NA

    First recorded

Oct 2007

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Institute for Clinical Evaluative Sciences
  • Ontario Ministry of Health and Long Term Care
  • Unity Health Toronto
Data source: Unity Health Toronto

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations