deltatrials
Completed PHASE3 INTERVENTIONAL 2-arm NCT00526474

Trial to Assess the Effects of Vorapaxar (SCH 530348; MK-5348) in Preventing Heart Attack and Stroke in Patients With Atherosclerosis (TRA 2°P - TIMI 50) (P04737)

A Multicenter, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Safety and Efficacy of SCH 530348 in Addition to Standard of Care in Subjects With a History of Atherosclerotic Disease: Thrombin Receptor Antagonist in Secondary Prevention of Atherothrombotic Ischemic Events (TRA 2°P - TIMI 50)

Sponsor: Merck Sharp & Dohme LLC

Updated 13 times since 2017 Last updated: Aug 22, 2018 Started: Sep 1, 2007 Primary completion: Dec 1, 2011 Completion: Dec 1, 2011
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

A PHASE3 clinical study on Atherosclerosis and Cerebrovascular Accident, this trial is completed. The trial is conducted by Merck Sharp & Dohme LLC and has accumulated 13 data snapshots since 2007. Cardiovascular trials of this type often inform treatment guidelines for long-term patient management.

Status Flow

~Jan 2017 – ~Feb 2017 · 31 days · monthly snapshot~Feb 2017 – ~Jun 2017 · 4 months · monthly snapshot~Jun 2017 – ~Jun 2018 · 12 months · monthly snapshot~Jun 2018 – ~Oct 2018 · 4 months · monthly snapshot~Oct 2018 – ~Jan 2021 · 27 months · monthly snapshot~Jan 2021 – ~Dec 2021 · 11 months · monthly snapshot~Dec 2021 – ~Jun 2022 · 6 months · monthly snapshot~Jun 2022 – ~Dec 2022 · 6 months · monthly snapshot~Dec 2022 – ~Jan 2023 · 31 days · monthly snapshot~Jan 2023 – ~Jul 2024 · 18 months · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – ~Feb 2025 · 5 months · monthly snapshot~Feb 2025 – present · 16 months · monthly snapshot

Change History

13 versions recorded
  1. Feb 2025 — Present [monthly]

    Completed PHASE3

  2. Sep 2024 — Feb 2025 [monthly]

    Completed PHASE3

  3. Jul 2024 — Sep 2024 [monthly]

    Completed PHASE3

  4. Jan 2023 — Jul 2024 [monthly]

    Completed PHASE3

  5. Dec 2022 — Jan 2023 [monthly]

    Completed PHASE3

Show 8 earlier versions
  1. Jun 2022 — Dec 2022 [monthly]

    Completed PHASE3

  2. Dec 2021 — Jun 2022 [monthly]

    Completed PHASE3

  3. Jan 2021 — Dec 2021 [monthly]

    Completed PHASE3

  4. Oct 2018 — Jan 2021 [monthly]

    Completed PHASE3

  5. Jun 2018 — Oct 2018 [monthly]

    Completed PHASE3

  6. Jun 2017 — Jun 2018 [monthly]

    Completed PHASE3

  7. Feb 2017 — Jun 2017 [monthly]

    Completed PHASE3

  8. Jan 2017 — Feb 2017 [monthly]

    Completed PHASE3

    First recorded

Sep 2007

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Merck Sharp & Dohme LLC
  • The TIMI Study Group
Data source: Merck Sharp & Dohme LLC

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations

No location information available.