Completed PHASE3 INTERVENTIONAL 3-arm NCT00528970

A Study Evaluating Intravenous (IV) MOA-728 for the Treatment of Postoperative Ileus (POI) in Participants After Ventral Hernia Repair

A Multicenter, Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Study of Intravenous Methylnaltrexone (MOA-728) for the Treatment of Post Operative Ileus After Ventral Hernia Repair

Sponsor: Bausch Health Americas, Inc.

Conditions Ileus

Interventions MOA-728 Placebo

Updated 9 times since 2017 Last updated: Aug 12, 2019 Started: Oct 17, 2007 Primary completion: Feb 5, 2008 Completion: Feb 5, 2008

This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

A PHASE3 clinical study on Ileus, this trial is completed. The trial is conducted by Bausch Health Americas, Inc. and has accumulated 9 data snapshots since 2007. Longitudinal tracking of this trial contributes to a broader understanding of treatment development timelines.

Status Flow

Change History

9 versions recorded

Sep 2025 — Present [monthly]

Completed PHASE3
Sep 2024 — Sep 2025 [monthly]

Completed PHASE3
Jul 2024 — Sep 2024 [monthly]

Completed PHASE3
Jan 2021 — Jul 2024 [monthly]

Completed PHASE3
Oct 2019 — Jan 2021 [monthly]

Completed PHASE3

▶ Show 4 earlier versions

Jun 2019 — Oct 2019 [monthly]

Completed PHASE3
Jun 2018 — Jun 2019 [monthly]

Completed PHASE3
Feb 2017 — Jun 2018 [monthly]

Completed PHASE3
Jan 2017 — Feb 2017 [monthly]

Completed PHASE3

First recorded

Oct 2007

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:

Bausch Health Americas, Inc.
Progenics Pharmaceuticals, Inc.

Data source: Bausch Health Americas, Inc.

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations

Adelaide SA, Australia , Albany, United States , Albuquerque, United States , Ann Arbor, United States , Augustenburger Platz 1, Germany , Baltimore, United States , Bellevue, United States , Bend, United States , Benton, United States , Bergamo, Italy and 85 more locations